Researchers at UConn Health used stem cells derived from patients with Angelman syndrome to identify the underlying cellular defects that cause the rare neurogenetic disorder, an important step in the ongoing search for potential treatments for Angelman and a possible cure. Up until now, scientists trying to understand why the brain cells of individuals with […]

Doctors seeking a cure for an aggressive form of multiple sclerosis keep chasing a mirage: no matter how well a drug works in the lab, it never seems to help many patients in the clinic. But after closely examining stem cells from patients and their families, researchers think they know why the drugs coming out of labs […]

In a report to be published in the journal Experimental Neurology on Feb 1, 2017, researchers in the Department of Neuroscience have determined that cells from patients with multiple sclerosis (MS) have an inherent defect in their ability to promote myelin – the brain tissue damaged in this disease.