The discipline of neuroscience examines nervous system function at numerous levels, incorporating a molecular and cellular viewpoint on the one hand and an integrative systems approach on the other. It is the goal of modern neuroscience research to integrate the two sides of this neurological coin into a consistent continuum, one that blends neurochemistry, developmental neurobiology, neuropharmacology, neurophysiology, neuroanatomy, and behavior neuroscience into a seamless intellectual construct capable of generating novel, testable hypotheses of how these individual disciplines are coordinated to produce the remarkable machine we call the nervous system. The Department of Neuroscience at UConn Health has applied these principles in the development of an equally integrated community of neuroscience investigators, with special strengths in the following areas of research: cellular and molecular, developmental, neuroinflammation and neuroimmunology, neurological disease, neurotransmission, sensory processing, and systems.