Recent advances from the Trakhtenberg lab have uncovered promising targetable regulators of neuronal self-repair, which fail to self-activate sufficiently in the injured mammalian CNS and thus require therapeutic activation. To find out more, see the below links to a Cover Page research article in Experimental Neurology, a research report in Brain Research, and research reports […]
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Targeting DKK1 Promotes Corneal Axonal Regeneration
In a first-of-its-kind breakthrough study targeting corneal Schwann cells for drug discovery, the Mohan Lab has identified Dickkopf-related protein 1 (DKK1) as a novel, druggable target for promoting axonal regeneration and restoring corneal sensitivity. Using a broad experimental strategy, the team defined DKK1’s role in corneal injury across two clinically relevant models: surgical lesions in […]
New Study from Crocker Lab on Aging Treatment
Crocker Lab publishes landmark study in PNAS on negative impact of popular anti-aging treatment. In the March 18 issue of Proceeding of the National Academy of Sciences, the Crocker lab have published a study describing an unexpected negative impact of two drugs, dasanitib and quercetin (D+Q), which has been used in combination to offset the […]