In a first-of-its-kind breakthrough study targeting corneal Schwann cells for drug discovery, the Mohan Lab has identified Dickkopf-related protein 1 (DKK1) as a novel, druggable target for promoting axonal regeneration and restoring corneal sensitivity. Using a broad experimental strategy, the team defined DKK1’s role in corneal injury across two clinically relevant models: surgical lesions in […]
Faculty
New Study from Crocker Lab on Aging Treatment
Crocker Lab publishes landmark study in PNAS on negative impact of popular anti-aging treatment. In the March 18 issue of Proceeding of the National Academy of Sciences, the Crocker lab have published a study describing an unexpected negative impact of two drugs, dasanitib and quercetin (D+Q), which has been used in combination to offset the […]
NIH CounterACT program R01 grant awarded to the Mohan lab
The NIH has awarded Royce Mohan, who is a professor of neuroscience at UConn Health, a new R01 grant to study the mechanisms of corneal damage and sensory loss caused by exposure to chemical threat agents. His research team, jointly led by co-investigator Paola Bargagna-Mohan, will advance state-of-the-art methods that combine transgenic and gene knockout […]