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Activation of macrophage TRPM2 and CD36 promotes atherosclerosis

Atherosclerosis is the major cause of ischemic heart disease and stroke, the leading causes of mortality worldwide. To develop better therapies, Dr. Yue’s group focuses on investigating the underlying mechanism of atherosclerosis, the root cause of cardiovascular diseases and brain stroke. The prominent feature of atherosclerosis is the formation of foam cells, the lipid-laden macrophages. Foam cells accelerate […]