Verma lab in collaboration of Bahal lab from Storrs campus has published their new finding about leveraging the  benefits of advanced gamma Peptic Nucleic Acid based miRNA-141 inhibitor for the treatment of ischemic stroke. Their finding was published in the journal Molecular Therapy: Nucleic Acid.  In this work first author Dr Sanjeev Kumar Yadav found that gamma PNA based substitution not only improves efficacy for miR-141 inhibition, but this inhibitor is highly potent and provides long term recovery in mouse model of ischemic stroke. This inhibitor also reduces inflammation of the brain after stroke . Their work also found place in UConn today news https://today.uconn.edu/2024/10/uconn-researchers-working-to-extinguish-inflammatory-fire-stroke-causes-in-the-brain/

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