Month: August 2024

Dr. Xiong wrote invited review at Trends in Molecular Medicine

Mutations in leucine-rich-repeat kinase 2 (LRRK2) are the most common causes of Parkinson’s disease (PD) up to date. Dysfunction in LRRK2 enzymatic activities and elevated protein levels are associated with the disease. How is LRRK2 activated, and what downstream molecular and cellular processes does LRRK2 regulate? Addressing these questions is crucial to decipher the disease […]