04-05-22 Last April 2021, Les Loew and five other faculty were recognized for their achievement of Board of Trustees Distinguished Professor. Today, Les and his colleagues received their medals and plaques for this most notable achievement. Congratulations to Les and his colleagues. CCAM is proud to have you as am amazing colleague Les, and grateful for all your contributions to science you have made over the course of your career.
03-02-22 A warm congratulations to Pedro for being one of 12 new inductees to the Connecticut Academy of Science and Engineering (CASE). Pedro, and fellow inductees, will be honored virtually at the Academy’s 47th annual meeting on May 26, 2022. To learn more about his latest achievement please read “Twelve UConn Faculty Members Elected to Connecticut Academy of Science and Engineering“, in UConn TODAY.
02-18-22. Congratulations to Boris Slepchenko on his latest publication with CCAM alumnus Masoud Nickaeen, A model of actin-driven endocytosis explains differences of endocytic motility in budding and fission yeast. In this article they showed that a molecularly explicit model of forces exerted by actin filaments on endocytic invaginations explains the differences in endocytic invaginations between budding and fission yeast.
12-11-21. Congratulations to Drs. Ji Yu and Ud Din who recently published a paper in Scientific Reports. The paper, “Training a deep learning model for single‑cell segmentation without manual annotation” presents a convolutional neural network (CNN) segmentation method that uses a marker-controlled segmentation algorithm that is suitable for use where cells are tightly packed together. (Training a deep learning model for single-cell segmentation without manual annotation. Scientific reports 2021 Dec;11(1):23995.)
Single-cell segmentation of bright-field (left) and fluorescence (middle) microscopy images using a neural-network model trained in a self-supervised fashion. Image on the right shows the consistency of the two segmentation results.
12-17-21. Pedro recently published another paper, MYC dosage compensation is mediated by miRNA-transcription factor interactions in aneuploid cancer. The paper, published in iScience, identifies a network of transcription factors and microRNAs that compensate for MYC gene over-expression and allows certain cancerous cells to survive in those conditions. This was discovered with a new computational method that uses COPASI and the findings were confirmed experimentally. Congratulations Pedro!