CCAM at UConn Health
Is developing new approaches for in vivo measurements and manipulation of molecular events within the cell, and new computational approaches for organizing such data into quantitative models.
CCAM integrates new microscope technologies for making quantitative in vivo live cell measurements with new physical formulations and computational tools that will produce spatially realistic quantitative models of intracellular dynamics.
To investigate the relationships between experimental and computational worlds, we use a tripartite approach described as:
- Measure - develop new tools for measuring spatially resolved dynamic behavior of molecules in cells.
- Model - develop new methods for spatial modeling of biological systems.
- Manipulate - develop new techniques for manipulating the spatial distribution of molecules in living cells.
These three analytical approaches, (measurement, modeling and manipulation) are integrated and interdependent, e.g., models generate predictions that can be validated with new measurements, as well as experimental approaches that manipulate intracellular signals and structures. These approaches allow us to tackle fundamental questions of how the spatial organization of molecules in cell is established and how it is utilized to control cell function. CCAM hosts a confluence of expertise in physics, chemistry, experimental cell biology and software engineering immersed in a biomedical research setting that values interdisciplinary collaborations, and our Training Program in Cell Analysis and Modeling provides a new model for interdisciplinary training in cell biology. CCAM is the home of the Virtual Cell, a computational environment for cell biological modeling developed as a NIH-designated National Resource, and also hosts a variety of projects in biophotonics and live cell microscope imaging methods as well as a state-of-the-art user microscopy facility for nonlinear, confocal, and widefield microscopy.
Upcoming Events
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Mar
5
CAM Meeting - BPS Review12:00pm
CAM Meeting - BPS Review
Friday, March 5th, 2021
12:00 PM - 01:00 PM
Other Virtual
CAM Meeting
Review of the 2021 BPS Virtual MeetingContact Information: Tiffany - jespersen@uchc.edu
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Mar
12
CAM Meeting - Ann Cowan12:00pm
CAM Meeting - Ann Cowan
Friday, March 12th, 2021
12:00 PM - 01:00 PM
Other Virtual
CAM Meeting
Speaker: Ann Cowan
Title: TBAContact Information: Tiffany - jespersen@uchc.edu
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Mar
18
CCAM Seminar Series - Sulagna Das12:00pm
CCAM Seminar Series - Sulagna Das
Thursday, March 18th, 2021
12:00 PM - 01:00 PM
UConn Health Virtual
CCAM Seminar Series
Host: Ji Yu
Speaker: Sulagna Das, Research Assistant Professor, Department of Anatomy & Structural Biology
Title: TBAContact Information: Tiffany; jespersen@uchc.edu
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Mar
19
CAM Meeting - Boris Slepchenko12:00pm
CAM Meeting - Boris Slepchenko
Friday, March 19th, 2021
12:00 PM - 01:00 PM
Other Virtual
CAM Meeting
Speaker: Boris Slepchenko
Title: TBAContact Information: Tiffany - jespersen@uchc.edu
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Mar
26
CAM Meeting - Kshitiz12:00pm
CAM Meeting - Kshitiz
Friday, March 26th, 2021
12:00 PM - 01:00 PM
Other Virtual
CAM Meeting
Speaker: Kshitiz
Title: TBAContact Information: Tiffany - jespersen@uchc.edu
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Inclusivity Statement
CCAM is committed to fostering an inclusive and tolerant research environment. We support students and faculty of all races, religions, ethnicities, differing physical abilities, sexual orientations, and gender identities.
UConn maintains a number of resources to promote inclusivity and to report complaints:
Office of Institutional Equity
Ombuds Office
Dean of Students Office Bias Reporting
Office for Diversity and Inclusion
School of Medicine Office of Multicultural and Community Affairs