Month: January 2022

Pedro Mendes Publication using COPASI

12-17-21. Pedro recently published another paper,  MYC dosage compensation is mediated by miRNA-transcription factor interactions in aneuploid cancer. The paper, published in iScience, identifies a network of transcription factors and microRNAs that compensate for MYC gene over-expression and allows certain cancerous cells to survive in those conditions. This was discovered with a new computational method that uses COPASI and the findings were confirmed experimentally. Congratulations Pedro!

Mendes Publication

12-15-21. Congratulations to Pedro Mendes on a new publication, Understanding Lactobacillus paracasei
and Streptococcus oralis biofilm interactions through agent-based modeling
, published in mSphere 6:e0087521. Along with other UConn Health investigators, they studied the interactions between two bacterial species that form biofilms in the oral cavity. The research combined experiments and agent-based simulations to understand the mechanism of interaction.