12-11-21. Congratulations to Drs. Ji Yu and Ud Din who recently published a paper in Scientific Reports. The paper, “Training a deep learning model for single‑cell segmentation without manual annotation” presents a convolutional neural network (CNN) segmentation method that uses a marker-controlled segmentation algorithm that is suitable for use where cells are tightly packed together. (Training a deep learning model for single-cell segmentation without manual annotation. Scientific reports 2021 Dec;11(1):23995.)
Single-cell segmentation of bright-field (left) and fluorescence (middle) microscopy images using a neural-network model trained in a self-supervised fashion. Image on the right shows the consistency of the two segmentation results.