Dr. Kailasan Vanaja’s Paper Published in Nature Communications

Congratulations to Dr. Sivapriya Kailasan Vanaja for having her paper, “A bacterial autotransporter impairs innate immune responses by targeting the transcription factor TFE3 published in the journal Nature Communications. The paper first authored by Dr. Atri Ta, a postdoctoral fellow in the Kailasan Vanaja lab, identified a novel autotransporter protein secreted by Enterohemorrhagic Escherichia coli that functions as a suppressor of host type I interferon defense. The findings from this study provide insights into the mechanisms by which bacterial pathogens diminish the host innate immune responses to successfully establish an infection.


Dr. Kailasan Vanaja, Dr. Ta