Congratulations to Dr. Sivapriya Kailasan Vanaja for having a paper from her lab, Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS, accepted for publication in Science Immunology. The paper first authored by Morena Mendonca, a postdoctoral fellow in the Kailasan Vanaja lab, demonstrates that Shiga toxin, a primary virulence factor of Enterohemorrhagic Escherichia coli, suppresses cytosolic LPS-mediated inflammasome responses by inhibiting the cleavage of gasdermin D. The findings from this study provide insights into the mechanisms by which bacterial pathogens modulate the host innate immune responses to successfully establish an infection.
Congratulations to Dr. Penghua Wang on the award of his R21 grant through the National Institute of Allergy and Infectious Diseases entitled, A critical role for UBXN3B in IgG homeostasis and maternal transfer.
Dr. Beiyan Zhou has been named the winner of the 2020 Women of Innovation® Research Innovation and Leadership category from the Connecticut Technology Council and Connecticut Center for Advanced Technology. Dr. Zhou was selected by a panel of judges from over 150 nominations. Read more.