Month: March 2024

Dr. Sivapriya Kailasan Vanaja and Ms. Skylar Wright’s Paper Published in Cell Reports

Congratulations Dr. Sivapriya Kailasan Vanaja and Ms. Skylar Wright for having their paper, “A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis”  published in the journal Cell Reports. The paper, first-authored by Ms. Skylar Wright, a graduate student, identified a novel molecular mechanism by which a clinically significant human pathogen, Enterohemorrhagic E. coli, utilizes its virulence factor, Shiga toxin, to effectively suppress host protective noncanonical inflammasome responses.

Dr. Kailasan Vanaja and Skylar Wright