Dr. Sivapriya Kailasan Vanaja and Ms. Skylar Wright’s Paper Published in Cell Reports

Congratulations Dr. Sivapriya Kailasan Vanaja and Ms. Skylar Wright for having their paper, “A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis”  published in the journal Cell Reports. The paper, first-authored by Ms. Skylar Wright, a graduate student, identified a novel molecular mechanism by which a clinically significant human pathogen, Enterohemorrhagic E. coli, utilizes its virulence factor, Shiga toxin, to effectively suppress host protective noncanonical inflammasome responses.

Dr. Kailasan Vanaja and Skylar Wright