Congratulations to Dr. Kepeng Wang for having his paper, “Cancer immunotherapy with enveloped self-amplifying mRNA CARG-2020 that modulates IL-12,  IL-17 and PD-L1 pathways to prevent tumor recurrence” published in Acta Pharmaceutica Sinica B (APSB). The paper describes a novel oncolytic viral therapy for cancers that incorporates payloads targeting IL-12, IL-17, and PD-L1 signaling. Successful eradication of established colon and liver tumors in mouse models points to the agent’s potential in future clinical use in humans. Former postdoctoral fellow Dr. Ju Chen from Dr. Kepeng Wang’s lab is the leading author of the publication.  Please use this link to access the publication: https://www.sciencedirect.com/science/article/pii/S2211383523003416

Congratulations to Dr. Zhichao Fan for receiving another Cystic Fibrosis Foundation grant entitled, “Impact of CFTR in monocyte adhesion and integrin function”.  Dr. Beiyan Zhou and Dr. Anthony Vella from the Department of Immunology and Dr. Wenqi Gan from the Department of Public Health Sciences serve as Co-Investigators.