DARPA Funds Whole-Cell Discovery Workflow for E. coli

September 27, 2024. Dr. Eran Agmon, PI at UConn Health, has received a DARPA grant to develop an innovative workflow for discovering unknown gene functions in whole-cell models of E. coli. The project, part of DARPA’s Discovering Unknown Function (DUF) initiative, will harness UConn’s HPC resources to simulate thousands of model variants, enhancing our understanding of E. coli gene functionality. This scalable workflow will leverage modular simulation, probabilistic data analysis, and advanced inference techniques to systematically address gaps in gene function knowledge.


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