March 18, 2025.  Dr. Eran Agmon recently presented his research at the AFOSR-sponsored workshop, Advancing Space Biotechnology through Whole-Cell Models and Functional Annotation. The symposium brought together leaders in synthetic biology, genomics, and computational modeling to explore how whole-cell models can drive innovation in space-based biotechnology. Dr. Agmon presented his work on building a multiscale simulation of Escherichia coli, using the Vivarium framework. The platform integrates diverse submodels—spanning gene regulation, metabolism, and cell growth—into an extensible whole-cell simulation environment. His presentation highlighted how Vivarium’s architecture supports interoperability across simulation methods, paving the way for next-generation virtual cells that can inform biomanufacturing to support long-term space missions.