08-14-2023. CCAM Faculty Yan, Acker and Loew publish a paper on near infrared fluorescent voltage sensors in PNAS. The organic synthesis of the new ElectroFluor dyes is described as well as an application to optogenetic activation and sensing of cardiac action potentials in live mouse hearts.
Yan, P.; Acker, C. D.; Biasci, V.; Judge, G.; Monroe, A.; Sacconi, L.; Loew, L. M. (2023). Near-Infrared Voltage-Sensitive Dyes Based on Chromene Donor. Proceedings of the National Academy of Sciences, 120 (34), e2305093120.
https://www.pnas.org/doi/10.1073/pnas.2305093120