Caimano Lab
My research focuses on the pathogenic spirochetes Borrelia burgdorferi and Leptospira interrogans, the causative agents of Lyme disease and Leptospirosis, respectively. Our broad objective is to better understand the environmental signals, regulatory pathways and gene products required to maintain these unique bacteria within their enzootic and zoonotic life cycles and establish infection within the mammalian host.
Research in the Molecular Biology and Biophysics department focuses on understanding the proteins and pathways affected in human disease. From the structural biology of cancer drug targets to the mechanistic interplay between viruses and human cells, MBB labs study the basic molecular processes underlying human illnesses.
Our department can be divided into five thematic areas:
