2023 – 2024
Mondays at Noon, In-Person and via Webex
Link: https://uconnhealth.webex.com/uconnhealth/j.php?MTID=m28b132d5474ef646adbd92f651594f4
MBB Conference Room E2036
| Date | Presenter | Title |
| 8/28 | Graduate Student Meeting | |
| 9/4 | Labor Day | |
| 9/11 | JC – Emilie Korchak (Bezsonova Lab) | New insights into cancer: MDM2 binds to the citrullinating enzyme PADI4 |
| 9/12* | JC – Rachel Godek (Page Lab) | CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress |
| 9/18 | JC – Patricia Hare (Mok Lab) | Precise spatial structure impacts antimicrobial susceptibility of S. aureus in polymicrobial wound infections. |
| 9/25 | JC – Travis LaGree (Mok Lab) | Uropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcome |
| 10/2 | JC – Elizabeth Szabo (Heinen Lab) | WRN helicase and mismatch repair complexes independently and synergistically disrupt cruciform DNA structures |
| 10/9 | Indigenous People’s Day | |
| 10/10* | WIP – Gianluca Arianna (Korzhnev Lab) | “Characterizing Protein-Protein Interactions Within Translesion Synthesis” |
| 10/16 | JC – Caroline Guild (Heinen Lab) | Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia |
| 10/23 | JC – Jonathan Batchelder (Mok Lab) | Growth Arrest of Staphylococcus aureus Induces Daptomycin Tolerance via Cell Wall Remodeling |
| 10/24* | JC – Daniel Fairchild (Bezsonova Lab) | Structural and functional asymmetry of RING trimerization controls priming and extension events in TRIM5α autoubiquitylation |
| 10/30 | JC – Bethlehem Abebe (Chou Lab) | Structure of the class D GPCR Ste2 dimer coupled to two G proteins |
| 11/6 | JC – Brooke Dreyer (Page Lab) | Cryo-EM structures reveal native GABAA receptor assemblies and pharmacology |
| 11/7# | JC – Ruoyu Yang (Oh Lab) | Neutrophil extracellular traps enhance S. aureus skin colonization by oxidative stress induction and downregulation of epidermal barrier genes |
| 11/13 | JC – Dane Geddes -Buehre (Korzhnev Lab) | DNA double-strand break-derived RNA drives TIRR/53BP1 complex dissociation |
| 11/20 | Thanksgiving Recess | |
| 11/27 | JC – Angela Power (Mok Lab) | re-scheduled |
| 12/4 | JC – Tvesha Parikh (Page Lab) | A split-luciferase lysate-based approach to identify small-molecule modulators of phosphatase subunit interactions |
| 12/5# | JC – Alexander Radecki (Vargas Lab) | Secreted Akkermansia muciniphila threonyl-tRNA synthetase functions to monitor and modulate immune homeostasis |
| 12/11 | JC – Darien Levi Craft (Schuyler/Gryk Labs) | Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases |
| 12/19 | JC – Angela Power (Mok Lab) | re-scheduled |
| 1/8* | MBB Prelim Prep | |
| 1/9 | JC – Angela Power (Mok Lab) | A Second Role for the Second Messenger Cyclic-di-GMP in E. coli: Arresting Cell Growth by Altering Metabolic Flow |
| 1/15 | Martin Luther King’s Day | |
| 1/16* | JC – Mian Horvath (Oh Lab) | Probiotic-guided CAR-T cells for solid tumor targeting |
| 1/22 | WIP – Emilie Korchak (Bezsonova Lab) | Mutations in USP7 enzyme leading to Hao-Fountain syndrome |
| 1/29 | WIP – Rachel Godek (Page Lab) | Mechanisms of substrate recruitment in Phosphoprotein Phosphatases |
| 2/5 | WIP – Ruoyu Yang (Oh Lab) | Molecular mechanisms underlying Staphylococcus modulation of skin processes |
| 2/12 | ||
| 2/13* | WIP – Jonathan Batchelder (Mok Lab) | Stimulating metabolism and biosynthesis to sensitize tolerant Staphylococcus aureus to antibiotics |
| 2/19 | WIP – Shermeen Khan (Setlow MA Student) | Understanding the Impact and Function of Novel Integral Inner Membrane Proteins on Properties of Bacillus subtilis Spores |
| 2/26 | WIP – Bethlehem Abebe (Chou Lab) | Biochemical, Structural, and Genetic Analysis of Pheromone Receptors in Yeast |
| 2/27#* | WIP – Travis LaGree (Mok Lab) | Investigating metabolism of antibiotic-tolerant E. coli to fight recurrent urinary tract infections. |
| 3/4 | WIP – Dane Geddes-Buehre (Korzhnev Lab) | Structure, Dynamics, and Inhibition of Protein Complexes in Translesion Synthesis |
| 3/11 | Spring Recess | |
| 3/18 | WIP – Tvesha Parikh (Page Lab) | Defining the role of Calcineurin activity in the Regulation of Signaling and Disease |
| 3/25 | ||
| 3/26 | ||
| 4/1 | ||
| 4/8 | WIP- Patricia Hare (Mok Lab) | Metabolic Insights into Pseudomonas aeruginosa Fluoroquinolone Sensitivity and Persistence |
| 4/15 | WIP – Elizabeth Szabo (Heinen Lab) | Functional analysis of variants of uncertain significance in the MSH6 mismatch repair gene |
| 4/22 | WIP – Angela Power (Mok Lab) | Scratching the surface: solidifying substrates used for Staphylococcus aureus biofilm cultivation impact extracellular matrix composition and antibiotic tolerance |
| 4/29 | WIP – Caroline Guild (Heinen Lab) | Investigating Selective Advantage of Mismatch Repair Loss in Colonic Organoids |
| 5/6 | WIP – Mian Horvath (Oh Lab) | Microbiome Stimulation of Respiratory Epithelial Antiviral Innate Immunity |
| 5/13* | WIP – Alexander Radecki (Vargas Lab) | Investigating the mechanism of adaptive translational fidelity of Salmonella enterica |
| 5/20* | WIP – Sam Mahdi (Korzhnev Lab) | |
| 6/10* | WIP – Daniel Fairchild (Bezsonova Lab) | |
| 6/17 | WIP – Darien Levi Craft (Schuyler/Gryk Labs) |
* These dates are outside of the academic calendar.