2024 – 2025
Mondays at Noon, In-Person and via Webex
Link: https://uconnhealth.webex.com/uconnhealth/j.php?MTID=m28b132d5474ef646adbd92f651594f4
MBB Conference Room E2036
| Date | Presenter | Title |
| 8/26 | Graduate Student Meeting | |
| 9/2 | Labor Day | |
| 9/9 | JC – Rouyu Yang (Oh Lab) | An early-life microbiota metabolite protects against obesity by regulating intestinal lipid metabolism |
| 9/16 | JC – Caroline Guild (Heinen Lab) | Mismatch repair protein MLH1 suppresses replicative stress in BRCA2-deficient breast tumors |
| 9/23 | JC – Jonathan Batchelder (Mok Lab) | Staphylococcus aureus adapts to exploit collagen-derived proline during chronic infection |
| 9/30 | JC – Rachel Godek (Page Lab) | Maf1 phosphorylation is regulated through the action of prefoldin-like Bud27 on PP4 phosphatase in Saccharomyces cerevisiae |
| 10/7 | JC – Dillon Vannest (Caimano Lab) | Structural insights into the mechanism of protein transport by the Type 9 Secretion System translocon |
| 10/8# | JC/WIP – Bernd Simon | And what about NMR |
| 10/14 | Indigenous People’s Day | |
| 10/21 | JC – Bethlehem Abebe (Chou Lab) | Molecular architecture of the Gαi-bound TRPC5 ion channel |
| 10/22# | WIP – Dr. Nisha Mahey (Mok Lab post-doc) | Timing matters: recA facilitates DNA damage repair in S. aureus persisters following fluoroquinolone treatment – rescheduled – Info to follow |
| 10/28 | JC – Tvesha Parikh (Page Lab) | Structure of Calcineurin bound to PI4KA reveals dual interface in both PI4KA and FAM126A |
| 11/4 | JC – Alex Radecki (Vargas-Rodriguez Lab) | Prophage terminase with tRNase activity sensitives Salmonella enterica to oxidative stress |
| 11/5# | WIP- Mian Horvath (Oh Lab) | Microbiome Modulation of Respiratory Epithelial Innate Immunity |
| 11/11 | JC – Daniel Fairchild (Bezsonova/Weller Lab) | TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence |
| 11/18 | JC – Dane Geddes -Buehre (Korzhnev Lab) | Catalytic and noncatalytic functions of DNA polymerase κ in Translesion DNA synthesis |
| 11/25 | Thanksgiving Recess | |
| 12/2 | JC – Wen Liu (Chou Lab) | Structural basis of μ-opioid receptor targeting by a nanobody antagonist |
| 12/9* | WIP – Darien Craft (Schuyler/Gryk Lab) | Evaluating Metrics of Spectral Quality in Nonuniform Sampling |
| 12/16* | WIP – Elizabeth Szabo (Heinen Lab) | Functional Analysis of Variants in the MSH6 Mismatch Repair Gene |
| 12/23 – 30 | Winter Break | |
| 1/6 | MBB Prelim Prep | |
| 1/13 | WIP – Emilie Korchak (Bezsonova Lab) | Functional Spectrum of USP7 Pathogenic Variants in Hao-Fountain Syndrome: Insights into the Enzyme’s Activity, Stability, and Allosteric Modulation |
| 1/20 | Martin Luther King’s Day | |
| 1/27 | WIP – Wen Liu (Chou Lab) | Structure Basis and Regulatory Mechanism of Transmembrane Signaling through Guanylyl Cyclase Natriuretic Peptide Receptor 2
Unusual Binding of the Cyclic Peptide Goniodomin-A to Actin Filament Explains its Cell Toxicity |
| 2/3 | WIP – Daniel Fairchild (Bezsonova/Weller Lab) | Uncovering the Molecular Mechanisms that Drive PML-NB Formation in the Innate Immune Response |
| 2/11# | WIP – Ruoyu Yang (Oh Lab) | Genetically diverse Staphylococcus strains modulate skin process |
| 2/17 | President’s Day | |
| 2/24 | WIP – Bethlehem Abebe (Chou Lab) | Expression and Isolation of Membrane Proteins from Yeast and Native Sources: Pheromone Receptor Map3 and Fibroblast Growth Factor Receptor 3 (FGFR3) for Structural Studies
|
| 2/25 | WIP – Dillon Vannest (Caimano Lab) | The 8-stranded β-barrel outer membrane protein repertoire of Treponema pallidum, the syphilis spirochete |
| 3/10 | Spring Recess | |
| 3/17 | WIP – Caroline Guild (Heinen Lab) | Investigating selective advantage of mismatch repair loss in colonic organoids |
| 3/24 | WIP – Dane Geddes-Buehre (Korzhnev Lab) | Structure, Dynamics, and Inhibition of Protein Complexes in Translesion Synthesis |
| 3/31 | WIP – Alex Radecki (Vargas-Rodriguez Lab) | Elucidating the Function of Duplicated Tryptophanyl-tRNA Synthetase Genes in Salmonella enterica |
| 4/7 | ||
| 4/14 | WIP – Patricia Hare (Mok Lab) | DNA Damage in Fluoroquinolone-Treated Pseudomonas aeruginosa |
| 4/15 | WIP – Tvesha Parikh (Page Lab) | Active Site Recruitment is key for specific substrate recruitment of Calcineurin |
| 4/21 | WIP – Rachel Godek (Page Lab) | Defining the architecture and mechanisms of substrate recruitment by the PP2A family of phosphatases |
| 4/28 | WIP – Travis LaGree (Mok Lab) | Investigating the nutritional impact on fluoroquinolone sensitivity in uropathogenic E. coli strains using omics approaches |
| 5/5 | WIP – Angela Power (Mok Lab) | |
| 5/12* | WIP – Jonathan Batchelder (Mok Lab) |
* These dates are outside of the academic calendar.