Journal Club/Work-In-Progress

2025 – 2026

Mondays at Noon, In-Person and via Webex

Link: https://uconnhealth.webex.com/uconnhealth/j.php?MTID=m28b132d5474ef646adbd92f651594f4

MBB Conference Room E2036

 

Date Presenter Title
8/25 Graduate Student Meeting
9/1 Labor Day
9/8 JC – Rachel Godek (Page Lab) Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments
9/15 JC – Angela Cupo ( Page Lab) A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase reveals a role at metaphase kinetochores
9/22 JC – Hiep Nguyen (Peti Lab) Allosteric regulation of the tyrosine phosphatase PTP1B by a protein–protein interaction
9/29 JC – Gabby Soriano  (Vargas Lab) Automated orthogonal tRNA generation
10/6 JC – Wen Liu (Chou Lab) Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone
10/13 Indigenous People’s Day
10/20 WIP – Kate Bruder (Paulino Lab) Characterization of human Ankle2 LEM Domain and its Binding Partners in the Context of Zika Virus Infection
10/27 JC- Betty Abebe (Chou Lab)

Architecture and activation of single-pass transmembrane receptor guanylyl cyclase

11/3
11/10 WIP – Ruoyu Yang (Oh Lab) Multifactorial modulation of skin processes in Staphylococcus–skin interactions
11/17 JC – Byron Dillon Vannest (Caimano Lab) Binding of Fusobacterium nucleatum autotransporter adhesin CbpF to human CEACAM1 and CEACAM5: A Velcro model for bacterium adhesion
11/24 Thanksgiving Recess
12/1 WIP – Caroline McNaboe (Heinen Lab) “Investigating Selective Advantage of Mismatch Repair Loss in Colonic Organoids”
12/8* WIP – Alex Radecki (Vargas Lab) An auxiliary tryptophanyl-tRNA synthetase offers Salmonella enterica Typhimurium a fitness advantage
12/9 JC – Jipeng Yue (Mok Lab) Aquatic environment drives the emergence of cell wall-deficient dormant forms in Listeria
12/15* WIP – Daniel Fairchild  (Bezsonova/Weller Lab) Isoform-specific Recognition of G-Rich Nucleic Acid Sequences by Promyelocytic Leukemia Protein PML
12/22 – 29 Winter Break
1/12 MBB Prelim Prep
1/19 Martin Luther King’s Day
1/26 WIP – Tvesha Parikh (Page Lab) Investigating how SLiM crosstalk in the AKAP/RII signaling platform defines Calcineurin activity
2/2 WIP -Wen Liu (Chou Lab) Structure Basis and Regulatory Mechanism of Transmembrane Signaling through Guanylyl Cyclase Natriuretic Peptide Receptor 2.

Unusual binding of the Macrolide Goniodomin-A to Actin Filaments Explains its Cell Toxicity.

2/9 WIP – Angela Cupo ( Page Lab) Determining the roles of PP6 subunits in holoenzyme assembly
2/16 President’s Day
2/17# WIP – Dane Geddes-Buehre (Korzhnev Lab) Structure, Dynamics, and Inhibition of Protein Complexes in Translesion Synthesis
2/23 WIP – Gabby Soriano  (Vargas Lab) – VIRTUAL ONLY Investigating the Functional Differences of Human eEF1As in tRNA Aminoacylation and Their Role in Peripheral Neuropathies

Developing a Platform for Engineering Suppressor-tRNATrp

3/2 WIP – Hiep Nguyen ( Peti Lab) Elucidating the phosphatase-independent activity of the protein tyrosine phosphatase Shp2 in RAS/MAPK signaling
3/9 Spring Recess
3/16 WIP – Travis LaGree (Mok Lab) Sensitivity of uropathogenic Escherichia coli to topoisomerase inhibitors is modulated by changes to the nutrient environment
3/23 WIP – Angela Power (Mok Lab) How the External Environment Impacts the Physiology and Antibiotic Susceptibility of Recalcitrant Pathogens
3/30
4/6 WIP – Jipeng Yue (Mok Lab)
4/13 WIP – Rachel Godek (Page Lab)
4/20 WIP – Betty Abebe (Chou Lab)
4/27 WIP – Nisha Mahey (Mok Lab)
5/4 WIP – Byron Dillon-Vannest (Caimano Lab)
5/11* WIP – Gabriella Chatman (Chou Lab)

* These dates are outside of the academic calendar.