UPDATE: Due to Covid-19, the meetings below are currently being held virtually. Please click the link to connect to Webex at https://uconnhealth.webex.com/meet/koshychenthittayil
The Mathematics in Medicine journal club meets the first Tuesday of each month from 12 to 1 p.m. in the large conference room across the hall from CQM (Room U3071, 195 Farmington).
The purpose of the MiM journal club is to discuss articles that utilize novel (or, utilize in a novel way!) mathematical methods to approach problems in biomedicine and clinical practice.
Dates of previous and upcoming meetings are below.
If you would like to present a paper or have any questions about the journal club, please contact Sherli Koshy-Chenthittayil, koshychenthittayil@uchc.edu.
| Date | Speaker | Title |
| April 06, 2021 |
Shelby Wilson, PhD |
Social Organization and its Effects on Disease Spread (Abstract) |
| February 23, 2021 |
Christopher Strickland, PhD |
Using mechanistic models to advance theory in opioid addiction epidemiology (Abstract) |
Previous Journal Clubs
2020
| Date | Speaker | Title |
| March 3, 2020 | Henrique De Assis Lopes Ribeiro | Pattern formation and chaos in spatial ecological public goods games (Wakano et al. 2011). |
| January 7, 2020 | Lauren Marazzi | Control of multilayer biological networks and applied to target identification of complex diseases (Zheng et al. 2020) |
| February 4, 2020 | Bandita Adhikari | Elucidating Compound Mechanism of Action by Network Perturbation Analysis (Woo et al. 2015) |
2019
| Date | Speaker | Title |
| January 8, 2019 | Bandita Adhikari | Computational modeling of the crosstalk between macrophage polarization and tumor cell plasticity in the tumor microenvironment (Li_et al. 2018) |
| February 5, 2019 | Albin Salazar | Detection of gene communities in multi-networks reveal cancer drivers (Cantini et al. 2015) |
| March 12, 2019 | Lokendra Poudel | Impact of hydrogen bonding in the binding site between capsid protein and MS2 bacteriophage ssRNA (Poudel et al. 2017) |
| April 2, 2019 | Henrique De Assis Lopes Ribeiro | Stochastic cellular automata model of tumorous neurosphere growth: Roles of developmental maturity and cell death (Zupanc et.al 2019) |
| May 7, 2019 | Jason Cory Brunson | Network Tomography for Understanding Phenotypic Presentations in Aortic Stenosis (Casaclang-Verzosa et al. 2019) |
| June 4, 2019 | Amit Luthra | Conformational communication mediates the reset step in t6A biosynthesis (2019) (Amit Luthra et al. 2019)
Structure and mechanism of a bacterial t6A biosynthesis system (2018) (Amit Luthra et al. 2018) |
| November 12, 2019 | Joseph Masison | Emergence and selection of isoniazid and rifampin resistance in tuberculosis granulomas (Pienaar et.al 2018) |
| December 3, 2019 | Luis Sordo Vieira | Model credibility in Computational Biology |
2018
| Date | Speaker | Title |
| January 2, 2018 | Abhishekh Gupta | Drug Sensitivity Scoring; Past, Present and Future (abstract) |
| March 6, 2018 | Anna Konstorum | Measuring distance through dense-weighted networks: The case of hospital-associated pathogens |
| April 10, 2018 | Cory Brunson | Conventional versus topological data analysis for disease subtyping: cases of type-2 diabetes mellitus (summary, Li_etal_2015, Ahlqvist_etal_2018) |
| June 19, 2018 | Cory Brunson | Using administrative data and network analysis to characterize disparities in healthcare (Hollingsworth et al., 2015, Ghomrawi et al., 2018) |
| July 17, 2018 | Luis Sordo Vieira | Mathematical modeling of the impact of cytokine response of acute myeloid leukemia cells on patient prognosis (Stiehl et al.) |
| August 7, 2018 | Joseph Masison | Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective (Chifman et al., 2017) |
| September 11, 2018 | Russell Posner | Mathematical Modeling of Renal Physiology and Pathology: Past and Present (Stephenson_1978, Layton_2017) |
| October 9, 2018 | Lauren Marazzi | Linking drug target and pathway activation for effective therapy using multi-task learning (Yang et al) |
| November 13, 2018 | Anna Konstorum | Comparing two classes of biological distribution systems using network analysis (Papadopoulos et al) |
2017
| Date | Speaker | Title |
| January 3, 2017 | Byoungkoo Lee | Atlas of Cancer Signalling Network |
| February 7, 2017 | Albin Salazar | Dynamical and Structural Analysis of a T Cell Survival Network Identifies Novel Candidate Therapeutic Targets for Large Granular Lymphocyte Leukemia |
| March 7, 2017 | Cory Brunson | Power law distributions in empirical data (presentation slides) |
| May 2, 2017 | Evelien Schassfsma | Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation |
| June 6, 2017 | Jignesh Parmar | A cellular stress-directed bistable switch controls the crosstalk between autophagy and apoptosis |
| September 5, 2017 | Reinhard Laubenbacher | How to escape the cancer attractor: Rationale and limitations of multi-target drugs |
| October 10, 2017 | Pedro Mendes | The Control of Flux: 21 Years On |
| November 7, 2017 | Sherli Koshy-Chenthittayil | Imitation dynamics of vaccination behavior on social networks |
| December 5, 2017 | Luis Sordo Vieira | A p-Adic Model of DNA sequence and Genetic Code |
2016
| Date | Speaker | Title |
| September 6, 2016 | Cory Brunson | Modulus on graphs as a generalization of standard graph theoretic quantities (presentation slides) |
| October 4, 2016 | Anna Konstorum | Topological Strata of Weighted Complex Networks |
| November 1, 2016 | Bandita Adhikari | A Logical Model Provides Insights into T Cell Receptor Signaling |
| December 6, 2016 | Russell Posner | Regulation of Ovulation Number in Mammals (video) |