Mathematics in Medicine Journal Club

UPDATE: Due to Covid-19, the meetings below are currently being held virtually.  Please click the link to connect to Webex at https://uconnhealth.webex.com/meet/koshychenthittayil​

The Mathematics in Medicine journal club meets the first Tuesday of each month from 12 to 1 p.m. in the large conference room across the hall from CQM (Room U3071, 195 Farmington).​

The purpose of the MiM journal club is to discuss articles that utilize novel (or, utilize in a novel way!) mathematical methods to approach problems in biomedicine and clinical practice.

Dates of previous and upcoming meetings are below.

If you would like to present a paper or have any questions about the journal club, please contact Sherli Koshy-Chenthittayil, koshychenthittayil@uchc.edu.

Date Speaker Title
April 06, 2021

Shelby Wilson, PhD

Social Organization and its Effects on Disease Spread (Abstract)
February 23, 2021

Christopher Strickland, PhD

Using mechanistic models to advance theory in opioid addiction epidemiology
(Abstract)

Previous Journal Clubs

2020

Date Speaker Title
March 3, 2020 Henrique De Assis Lopes Ribeiro Pattern formation and chaos in spatial ecological public goods games (Wakano et al. 2011).
January 7, 2020 Lauren Marazzi Control of multilayer biological networks and applied to target identification of complex diseases (Zheng et al. 2020)
February 4, 2020 Bandita Adhikari Elucidating Compound Mechanism of Action by Network Perturbation Analysis (Woo et al. 2015)

2019

Date Speaker Title
January 8, 2019 Bandita Adhikari Computational modeling of the crosstalk between macrophage polarization and tumor cell plasticity in the tumor microenvironment​  (Li_et al. 2018)
February 5, 2019 Albin Salazar Detection of gene communities in multi-networks reveal cancer drivers (Cantini et al. 2015)
March 12, 2019 Lokendra Poudel Impact of hydrogen bonding in the binding site between capsid protein and MS2 bacteriophage ssRNA (Poudel et al. 2017)
April 2, 2019 Henrique De Assis Lopes Ribeiro Stochastic cellular automata model of tumorous neurosphere growth: Roles of developmental maturity and cell death (Zupanc et.al 2019)
May 7, 2019 Jason Cory Brunson Network Tomography for Understanding Phenotypic Presentations in Aortic Stenosis (Casaclang-Verzosa et al. 2019)
June 4, 2019 Amit Luthra Conformational communication mediates the reset step in t6A biosynthesis (2019) (Amit Luthra et al. 2019)

Structure and mechanism of a bacterial t6A biosynthesis system (2018) (Amit Luthra et al. 2018)

November 12, 2019 Joseph Masison Emergence and selection of isoniazid and rifampin resistance in tuberculosis granulomas (Pienaar et.al 2018)
December 3, 2019 Luis Sordo Vieira Model credibility in Computational Biology

2018

Date Speaker Title
January 2, 2018 Abhishekh Gupta Drug Sensitivity Scoring; Past, Present and Future (abstract)
March 6, 2018 Anna Konstorum Measuring distance through dense-weighted networks: The case of hospital-associated pathogens
April 10, 2018 Cory Brunson Conventional versus topological data analysis for disease subtyping: cases of type-2 diabetes mellitus (summary, Li_etal_2015Ahlqvist_etal_2018)
June 19, 2018 Cory Brunson Using administrative data and network analysis to characterize disparities in healthcare (Hollingsworth et al., 2015, Ghomrawi et al., 2018)
July 17, 2018 Luis Sordo Vieira Mathematical modeling of the impact of cytokine response of acute myeloid leukemia cells on patient prognosis (Stiehl et al.)
August 7, 2018 Joseph Masison Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective (Chifman et al., 2017)
September 11, 2018 Russell Posner Mathematical Modeling of Renal Physiology and Pathology: Past and Present (Stephenson_1978Layton_2017)
October 9, 2018 Lauren Marazzi Linking drug target and pathway activation for effective therapy using multi-task learning (Yang et al)
November 13, 2018 Anna Konstorum Comparing two classes of biological distribution systems using network analysis (Papadopoulos et al)

2017

Date Speaker Title
January 3, 2017 Byoungkoo Lee Atlas of Cancer Signalling Network
February 7, 2017 Albin Salazar Dynamical and Structural Analysis of a T Cell Survival Network Identifies Novel Candidate Therapeutic Targets for Large Granular Lymphocyte Leukemia
March 7, 2017 Cory Brunson Power law distributions in empirical data (presentation slides)
May 2, 2017 Evelien Schassfsma Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
June 6, 2017 Jignesh Parmar A cellular stress-directed bistable switch controls the crosstalk between autophagy and apoptosis
September 5, 2017 Reinhard Laubenbacher How to escape the cancer attractor: Rationale and limitations of multi-target drugs
October 10, 2017 Pedro Mendes The Control of Flux: 21 Years On
November 7, 2017 Sherli Koshy-Chenthittayil Imitation dynamics of vaccination behavior on social networks
December 5, 2017 Luis Sordo Vieira A p-Adic Model of DNA sequence and Genetic Code

2016

Date Speaker Title
September 6, 2016 Cory Brunson Modulus on graphs as a generalization of standard graph theoretic quantities (presentation slides)
October 4, 2016 Anna Konstorum Topological Strata of Weighted Complex Networks
November 1, 2016 Bandita Adhikari A Logical Model Provides Insights into T Cell Receptor Signaling
December 6, 2016 Russell Posner Regulation of Ovulation Number in Mammals (video)