The Molecular Biology and Biochemistry Graduate Program offers complete and state-of-the-art research facilities within the Department of Molecular Biology and Biophysics with equipment and expertise for genetic, biochemical, molecular, cellular, structural and biophysical investigation. Within the department are facilities for cell culture, fermentation systems for high volume growth of bacteria and yeast, FPLC and HPLC, and a biophysics core facility which is equipped with a circular dichroism spectropolarimeter, an isothermal titration calorimeter, and multi-angle laser light scattering facilities. The department also houses the UConn Health NMR Structural Biology Facility, which includes cryoprobe-equipped 400, 500, 600 and 800 MHz NMR spectrometers. The department also houses the UConn Health Structural Biology Computational Facility, which includes a bank of Mac and Linux desktop computers connected to ultra-fast servers with the latest structural biology software. Facilities are also available for confocal laser scanning microscopy and low-light-level imaging microscopy in the state-of-the-art Center for Cell Analysis and Modeling. Additional facilities include electron microscopy, mass spectroscopy, DNA oligonucleotide synthesis and sequencing, microarray technology, and a transgenic mouse facility.