The research in the Finck Laboratory focuses on various pediatric and neonatal diseases that originate from congenital defects, preterm birth, accidental injuries and cancer. The focus of our work began with pediatric lung disease and utilizing stem cells and de-cellularized lung scaffolds to study and potentially treat pediatric lung diseases. We have now expanded our research interested into esophageal defects due to atresia, caustic injuries and cancer. We are now evaluating the use of synthetic polymers and scaffolding as a potential therapeutic option for these conditions. Lastly, we are also interested in pediatric solid tumors and how refractory populations persist in the tumor despite standard of care chemotherapy. We are investigating the mechanisms and pathways responsible for stem-like cells in the tumor being refractory to treatment and how the genetic expression profile changes after treatment.