Research & Clinical Trials | Hartford HealthCare | CT

Dissecting Aneurysm in Cervical Artery Dissection: Insights From the STOP-CAD Study
Khan M, Keser Z, Shu L, Lee E, Ho M, Klein P, Mallick D, Griffin K, Mandel D, Leker RR, Metanis I, Krishnaiah B, Omran S, Shahripour RB, Bakradze E, Henninger N, Engelter ST, Heldner MR, Antonenko K, Siegler JE, Marto JP, Rothstein A, Khazaal O, Nolte CH, Crandall R, Lester E, Nehme A, Mac Grory B, Ghannam M, Almajali M, Elnazeir M, Al Kasab S, Asad D, Balabhadra A, Fonseca AC, Cruz D, Romoli M, Saleh Velez F, Simpkins AN, Sen S, Zedde M, Samaniego EA, Zubair A, Stretz C, Kam W, Abdalkader M, Yaghi S, Nguyen TN. Dissecting Aneurysm in Cervical Artery Dissection: Insights From the STOP-CAD Study. Stroke. 2026 Apr;57(4):865-875. doi: 10.1161/STROKEAHA.125.054847. Epub 2026 Jan 29. PMID: 41608793.

Strategic endovascular approach for a rare type IVa perimedullary spinal arteriovenous fistula
Miller EA, Burke SM, Burch TG, Kureshi IU, Mehta T. Strategic endovascular approach for a rare type IVa perimedullary spinal arteriovenous fistula. J Neurointerv Surg. 2026 Aug 17;18(9):1956-1959. doi: 10.1136/jnis-2026-024967. PMID: 42020301.

Middle Meningeal Artery Embolization With n-Butyl Cyanoacrylate in Patients With Chronic Subdural Hematoma: A Randomized Clinical Trial
Kellner CP, Rai AT, Shoirah H, Srinivasan VM, Gupta R, Starke RM, Al-Mufti F, Matouk CC, Yim B, Fusco MR, Wan J, Liptrap E, Bhuva P, Grandhi R, Cerejo R, Liu JJ, Cherian J, Zhang Q, Kaminsky I, Prestigiacomo CJ, Orru' E, Lin E, Howington J, Evans A, Mehta T, Boo S, Finch I, Liu T, Chitale R, Majidi S, Jankowitz BT; MEMBRANE Study Group. Middle Meningeal Artery Embolization With n-Butyl Cyanoacrylate in Patients With Chronic Subdural Hematoma: A Randomized Clinical Trial. JAMA Neurol. 2026 Aug 1;83(8):749-758. doi: 10.1001/jamaneurol.2026.1542. Erratum in: JAMA Neurol. 2026 Aug 1;83(8):827. doi: 10.1001/jamaneurol.2026.2457. PMID: 42295790; PMCID: PMC13270299.

Impaired Perfusion and Early Ischemic Stroke Recurrence in Symptomatic Intracranial Atherosclerosis: BIORISK ICAS Study
Yaghi S, Khan F, Lewis S, Stipanovich A, Choi R, Baker R, Al Kasab S, Abu Qdais A, Yaddanapudi SS, Sultana S, Khan M, Malik M, Klaas J, Bakradze E, Aemaz Ur Rehman M, Leon Guerrero C, Ressler HW, Saleh Velez FG, Owens C, Pinto CB, McCullough-Hicks M, Cooper D, Parameswaran Pillai A, Hariharan P, Alam S, Mayer M, Heldner MR, Kugler I, Antonenko K, Almiri W, Martins S, Secchi TL, Mantovani G, Rothstein A, Sloane K, Krishnaiah B, Alfred L, Elangovan C, Vishnu VY, Chandu M, Agarwal A, Romoli M, Marrone N, Vozzi S, Ghannam M, Elshikh M, Dibas M, Hou Y, Peshwe K, Tunguturi A, Marto JP, Duarte Armindo R, Frontera J, Kuohn L, AlMajali M, Zaidat OO, Barakat B, Khan N, Simpkins AN, Sen S, Coelho M, Sargento Fritas J, Sousa JA, Aguiar de Sousa D, Soares M, Cyntia Lima Fonseca Rodrigues A, Jhaveri A, Morsi RZ, Siegler J, Aziz YN, Harker P, Bhati S, Vassilopoulou S, Tountopoulou A, de Havenon A, Muddasani V, Henninger N, Tran H, Helenius J, Khasawneh M, Vellimana A, Apfel R, Molaie A, Mannino M, Terruso V, El Halabi T, Reda M, Tamer C, Klein P, Shu L, Khatri P, Furie K, Nguyen TN, Liebeskind DS, Prabhakaran S. Impaired Perfusion and Early Ischemic Stroke Recurrence in Symptomatic Intracranial Atherosclerosis: BIORISK ICAS Study. Stroke. 2026 Jan;57(1):96-106. doi: 10.1161/STROKEAHA.125.053160. Epub 2025 Oct 23. PMID: 41128719; PMCID: PMC12616403.

Cerebral Air Embolism Caused by Atrial-Esophageal Fistula Following Left Atrial Ablation
Mashayekhi M, Balabhadra A, Mehta T, Tarasaria K, Tunguturi A, Somerville D, Hou Y. Cerebral Air Embolism Caused by Atrial-Esophageal Fistula Following Left Atrial Ablation. Stroke. 2025 Aug;56(8):e195-e198. doi: 10.1161/STROKEAHA.124.050091. Epub 2025 Jul 28. PMID: 40720574.

Endovascular treatment of infectious intracranial aneurysms: A single-center experience.
Patel SD, Balabhadra AA, Miller EA, Gandhi IS, Patel N, Fowler J, Tunguturi A, Otite FO, Bruno C, Sussman E, Ollenschleger M, Mehta T.Brain Circ. 2025 Mar 21;11(1):24-29. doi: 10.4103/bc.bc_77_24. eCollection 2025 Jan-Mar.PMID: 40224557

Factors Associated With Stroke Recurrence After Initial Diagnosis of Cervical Artery Dissection. Stroke. 2025 Jun;56(6):1413-1421. doi: 10.1161/STROKEAHA.124.048215. Epub 2025 Mar 27.PMID: 40143807

Heterogeneity of State Stroke Center Certification and Designation Processes.
Feldmeier M, Kim AS, Zachrison KS, Alberts MJ, Shen YC, Hsia RY.Stroke. 2024 Apr;55(4):1051-1058. doi: 10.1161/STROKEAHA.123.045368. Epub 2024 Mar 12.PMID: 38469729

Antithrombotic Treatment for Stroke Prevention in Cervical Artery Dissection: The STOP-CAD Study.
Stroke. 2024 Apr;55(4):908-918. doi: 10.1161/STROKEAHA.123.045731. Epub 2024 Feb 9.PMID: 38335240

Intravenous Thrombolysis in Patients With Cervical Artery Dissection: A Secondary Analysis of the STOP-CAD Study. Neurology. 2024 Oct 8;103(7):e209843. doi: 10.1212/WNL.0000000000209843. Epub 2024 Sep 19.PMID: 39298709

Development and Validation of a Clinical Score to Predict Epilepsy After Cerebral Venous Thrombosis. Lindgren E, Asad SD, Al Kasab S, Almallouhi E, Frontera J, Rothstein A, Bakradze E, Omran SS, Henninger N, Kuohn L, Zubair A, Sharma R, Kerrigan D, Aziz Y, Mistry E, Zuurbier SM.JAMA Neurol. 2024 Dec 1;81(12):1274-1283. doi: 10.1001/jamaneurol.2024.3481.PMID: 39432281

Trans-radial spinal angiography: A single-center experience.
Quinn C, Masood K, Mehta T, Topiwala K, Grande A, Tummala R, Jagadeesan BD.Interv Neuroradiol. 2024 Apr;30(2):288-292. doi: 10.1177/15910199221135052. Epub 2022 Oct 26.PMID: 36299241

Higher blood glucose is associated with the severity of hemorrhagic transformation after endovascular therapy for stroke.
Aziz YN, Vagal V, Mehta TV, Siegler JE, Mistry AM, Yaghi S, Khatri P, Mistry EA.J Stroke Cerebrovasc Dis. 2024 Aug;33(8):107823. doi: 10.1016/j.jstrokecerebrovasdis.2024.107823. Epub 2024 Jun 14.PMID: 38880367

Blood Pressure Management After Endovascular Therapy for Acute Ischemic Stroke: The BEST-II Randomized Clinical Trial.
Mistry EA, Hart KW, Davis LT, Gao Y, Prestigiacomo CJ, Mittal S, Mehta T, LaFever H, Harker P, Wilson-Perez HE, Beasley KA, Krothapalli N, Lippincott E, Stefek H, Froehler M, Chitale R, Fusco M, Grossman A, Shirani P, Smith M, Jaffa MN, Yeatts SD, Albers GW, Wanderer JP, Tolles J, Lindsell CJ, Lewis RJ, Bernard GR, Khatri P.JAMA. 2023 Sep 5;330(9):821-831. doi: 10.1001/jama.2023.14330.PMID: 37668620

Large Core Thrombectomies: Are We Still Conflicted or Confident.
Mehta T, Gonzalez N.Stroke. 2023 Sep;54(9):2313-2315. doi: 10.1161/STROKEAHA.123.043845. Epub 2023 Jul 26.PMID: 37492971

Diagnosis, Workup, Risk Reduction of Transient Ischemic Attack in the Emergency Department Setting: A Scientific Statement From the American Heart Association.
Amin HP, Madsen TE, Bravata DM, Wira CR, Johnston SC, Ashcraft S, Burrus TM, Panagos PD, Wintermark M, Esenwa C; American Heart Association Emergency Neurovascular Care Committee of the Stroke Council and Council on Peripheral Vascular Disease.Stroke. 2023 Mar;54(3):e109-e121. doi: 10.1161/STR.0000000000000418. Epub 2023 Jan 19.PMID: 36655570

In ischemic stroke without large or medium vessel occlusion, tirofiban increased likelihood of an excellent outcome.
Alberts MJ. In ischemic stroke without large or medium vessel occlusion, tirofiban increased likelihood of an excellent outcome. Ann Intern Med. 2023 Oct;176(10):JC111. doi: 10.7326/J23-0074. Epub 2023 Oct 3. PMID: 37782919.

Interventional compared with medical management of symptomatic carotid web: A systematic review.
Patel SD, Otite FO, Topiwala K, Saber H, Kaneko N, Sussman E, Mehta TV, Tummala R, Hinman J, Nogueira R, Haussen DC, Liebeskind DS, Saver JL.J Stroke Cerebrovasc Dis. 2022 Oct;31(10):106682. doi: 10.1016/j.jstrokecerebrovasdis.2022.106682. Epub 2022 Aug 20.PMID: 35998383

Predictors of Recurrent Venous Thrombosis After Cerebral Venous Thrombosis: Analysis of the ACTION-CVT Study.
Shu L, Bakradze E, Omran SS, Giles J, Amar J, Henninger N, Elnazeir M, Liberman A, Moncrieffe K, Rotblat J, Sharma R, Cheng Y, Zubair AS, Simpkins A, Li G, Kung J, Perez D, Heldner MR, Scutelnic A, von Martial R, Siepen B, Rothstein A, Khazaal O, Do D, Al Kasab S, Rahman LA, Mistry EA, Kerrigan D, Lafever H, Nguyen TN, Klein P, Aparicio HJ, Frontera JA, Kuohn L, Agarwal S, Stretz C, Kala N, ElJamal S, Chang A, Cutting S, Indraswari F, de Havenon A, Muddasani V, Wu T, Wilson D, Nouh A, Asad D, Qureshi A, Moore J, Khatri P, Aziz Y, Casteigne B, Khan M, Cheng Y, Mac Grory B, Weiss M, Ryan D, Vedovati MC, Paciaroni M, Siegler J, Kamen S, Yu S, Guerrero CL, Atallah E, De Marchis GM, Brehm A, Dittrich T, Psychogios M, Alvarado-Dyer R, Kass-Hout T, Prabhakaran S, Honda T, Liebeskind D, Furie K, Yaghi S. Predictors of Recurrent Venous Thrombosis After Cerebral Venous Thrombosis: Analysis of the ACTION-CVT Study. Neurology. 2022 Nov 22;99(21):e2368-e2377. doi: 10.1212/WNL.0000000000201122. Epub 2022 Sep 19. PMID: 36123126; PMCID: PMC9687409.

1. Evaluating the Diagnostic Utility of Brain MRI after Lobar Intracranial Hemorrhage, Amardeep Saund, MD, Ya-Huei Li, PhD, Ajay Tunguturi, MD, and Yan Hou, MD, Stroke Volume 56, Number Suppl_1 https://doi.org/10.1161/str.56.suppl_1.TP195
2. Predictors of Outcome in Subarachnoid Hemorrhage in the Pediatric Population, Smit D Patel, Anvesh Balabhadra, Fadar Otite, Ethan A Miller, Matthew N Jaffa, Ajay Tunguturi, Eric Sussman, Martin Ollenschleger, Mark J Alberts and Tapan Mehta, Originally published1 Feb 2024https://doi.org/10.1161/str.55.suppl_1.TP19Stroke. 2024;55: ATP19
3. Patel, Smit & Balabhadra, Anvesh & Otite, Fadar & Patel, Neel & Tunguturi, Ajay & Bruno, Charles & Sussman, Eric & Ollenschleger, Martin & Alberts, Mark & Mehta, Tapan. (2024). Abstract TP34: Outcomes and Trends of Subarachnoid Hemorrhage During the COVID-19 Pandemic. Stroke. 55. 10.1161/str.55.suppl_1.TP34.
4. Emmerson, Danison & Li, Ya-Huei & Tunguturi, Ajay & Nouh, Amre & Hou, Yan. (2024). Abstract TP249: A Real World Study of PFO Closure in Young Patients With Ischemic Stroke. Stroke. 55. 10.1161/str.55.suppl_1.TP249.
5. Miller, Ethan & Balabhadra, Anvesh & Varon, Alberto & Li, Ya-Huei & Emmerson, Danison & Patel, Smit & Sussman, Eric & Tunguturi, Ajay & Mehta, Tapan. (2024). Abstract TP141: Understanding Potential Limitations of CTP Imaging in Early Window Large Vessel Anterior Circulation Strokes. Stroke. 55. 10.1161/str.55.suppl_1.TP141.
6. Miller, Ethan & Balabhadra, Anvesh & Patel, Smit & Tunguturi, Ajay & Bruno, Charles & Sussman, Eric & Ollenschleger, Martin & Mehta, Tapan. (2023). Optimal Timeframe from Securing Mycotic Aneurysms to Cardiac Surgery: A Single Center Study. Stroke: Vascular and Interventional Neurology. 3. 10.1161/SVIN.03.suppl_2.182.
7. Patel, Smit & Balabhadra, Anvesh & Miller, Ethan & Tunguturi, Ajay & Bruno, Charles & Sussman, Eric & Ollenschleger, Martin & Mehta, Tapan. (2023). Abstract 183: Characteristics and Outcomes of Treated and Untreated Mycotic Aneurysms: A Single Center Study. Stroke: Vascular and Interventional Neurology. 3. 10.1161/SVIN.03.suppl_2.183.
8. Emmerson, Danison & Miller, Ethan & Elmashad, Ahmed & Tunguturi, Ajay & Nouh, Amre. (2023). Abstract TP114: Stroke Mimics: Uncovering The Truth In The History. Stroke. 54. 10.1161/str.54.suppl_1.TP114.
9. Neeharika Krothapalli, Smith Patel, Tapan Mehta, Ajay Tunguturi, Morphology of Mycoitc Aneurysms and Outcomes, 19th Annual meeting of Society of Neuro Interventional Surgery, July 25-22, 2022, Toronto, Ontario, Canada
10. Petechiae: An Atypical Initial Presentation of Seizure, Shivani Sodani, Musab Zorlu, Hasmik Amirjanyan, Swetha Ade, Ajay Tunguturi, 74th American Academy of Neurology Annual Meeting, April 7th, Seattle, Washington 2022