Cognitive Remediation of Cognitive Control in Late-Life Depression

Do you have concern over your thinking and memory? Would you like to participate in a study on cognitive fitness?

UConn Health study investigates effects of brain training treatment on thinking, memory, and mood. We are recruiting men and women over 60 who are currently being treated with antidepressants. We want to understand whether engaging in cognitively stimulating activities (e.g., brain games, watching educational videos, reading) can improve memory, thinking, and symptoms of depression in older adults.

Participation involves:

  • Interviews and evaluations.
  • Testing of thinking and memory.
  • Optional MRI brain scans.
  • No cost for participation.
  • 32-40 hours of brain-training exercises over 4-6 weeks. Subjects will be randomly assigned to 1 of 2 cognitive fitness programs.
  • All appointments and training exercises, except for optional MRIs, are completed remotely from your home.

    Payment to participants includes $40 at completion of each of the two assessment visits and $40 at completion of each of two optional MRI visits for a total of up to $160 for the 14-month study.

    Principal Investigator: Kevin Manning, Ph.D., Department of Psychiatry

    IRB Number: 21-046-2

    Enrollment end date: August 1, 2023

    To learn more about this study, call Dr. Manning at 860-679-2272.