Services Consultation Design and Generation of Genetically Modified Mice by CRISPR and ES Cell Technology Design and Preparation of Targeting Vectors by BAC Recombineering Import Mouse Lines by Embryo Transfer In Vitro Fertilization Mouse Model Management Mouse Embryo Cryopreservation PCR Genotyping Rederivation of Contaminated Mouse Lines Transgenic Mice by DNA Pronuclear Microinjection