1. The Center for Mouse Genome Modification (CMGM) will invoice you for the preparation and testing of CRISPR/Cas9 reagents including donor DNA at the time of the first session of microinjections (typically 1 month into the project).a
2. Approximately 2 to 3 months after that, we should have the initial genotyping results and will send you an update on the project. We will invoice you for the microinjections when we identify positive F0 miceb. If no F0 mice are identified after genotyping 50 pups, we will invoice you for half the cost of the microinjection to cover part of our expenses. At that point, we will discuss the status of the project with you, and you will have the option to terminate the project at no additional cost. If the PI decides to withdraw the project after microinjections have started, but before 50 pups are genotyped, we will invoice you for half the cost of the microinjection.
3. We will invoice you for the genotyping for the project after F1 mice are identified.
a. Projects for which any of the reagents are not prepared or purchased by the CMGM will be accepted on a case-by-case basis only.
b. Animal housing will be paid by the investigator after F0 pups are weaned. For external investigators, this will be a flat fee of $2,500. For internal investigators, you will be charged by the Center for Comparative Medicine (CCM) for all cage per diems after F0 pups are weaned.
We will make sure the PI understands this policy and agrees to the quote before beginning a project.
For internal investigators, we will get FOAPAL and billing info from the PI at the time of the quote agreement.
For external investigators, we will get a P.O. at the time of the quote agreement.