The Center for Mouse Genome Modification (CMGM) at UConn Health provides design and generation of genetically modified mice and other services.
We have successfully used CRISPR to generate KO, KI (insertions of DNA fragments up to 9kb), point mutations, precision deletions (removal of specific introns), and other novel mouse strains. See our publications for examples. We deliver positive F1 mice to ensure successful germline transmission and deliver simple PCR genotyping assay. Contact us to discuss the creation of your new CRISPR today!