Relevant Background Literature

Age and Aging as Clinical and Social Constructs

How “old age” was withdrawn as a diagnosis from ICD-11.pdf

 

Biomarkers of Aging

A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup.pdf

A tissue ubiquitous gene set for cellular senescence.pdf

BEST (Biomarkers, EndpointS, and other Tools) Resource.pdf

Biolearn, an open-source library for biomarkers of aging.pdf

Biomarkers of aging for the identification and evaluation of longevity interventions.pdf

Blood Biomarkers for Healthy Aging.pdf

ELISA and Multiplex Technologies for Cytokine Measurement in Inflammation and Aging Research.pdf

Frailty Screening Using the Electronic Health Record Within a Medicare Accountable Care Organization.pdf

KeepEX, a simple dilution protocol for improving extracellular vesicle yields from urine.pdf

Moving towards the detection of frailty with biomarkers: A population health study.pdf

Organ aging signatures in the plasma proteome track health and disease.pdf

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles.pdf

 

Clinical Trial Results Related to Older Adult Function

Multicomponent intervention to prevent mobility disability in frail older adults: randomised controlled trial (SPRINTT project).pdf

 

Frailty Measurement

Comparative Performance of Three Claims-Based Frailty Measures Among Medicare Beneficiaries.pdf

Development and Validation of an Intrinsic Capacity Score in the UK Biobank Study.pdf

How to construct a frailty index from an existing dataset in 10 steps.pdf

 

Gait Speed Measurement, Analysis, and Technology Implementation 

Factors influencing the clinical adoption of quantitative gait analysis technology with a focus on clinical efficacy and clinician perspectives: A scoping review.pdf

 

Including Underrepresented Populations in Research

GSA Towards a Quantified Science of Engagement and Recruitment.pdf

Health Equity through Clinical Research — Meeting the Challenge of Inclusion.pdf

Intergenerational Influence of African American, Caribbean and Hispanic/Latino Adults Regarding Decision to Participate in Health-Related Research.pdf

Improving Public Health Requires Inclusion of Underrepresented Populations in Research.pdf

 

Inclusivity in Research Across the Lifespan

Including Older Adults with Multiple Chronic Conditions in Research.pdf

Inclusion of Older Adults in Research: Ensuring Relevance, Feasibility, and Rigor.pdf

NIH Central Resource for Grants and Funding Information: Inclusion Across the Lifespan

NIH Inclusion Across The Lifespan Workshop.pdf

Recommendations for using the 5Ts Framework to support research inclusion across the lifespan

Representative enrolment of older adults in clinical trials: the time is now.pdf

 

Interventions to Enhance Independence

  • Subcategory: Exercise and Physical Activity

Physiological Principles of Exercise.pdf

 

Large Data Base Descriptions

Prospective study design and data analysis in UK Biobank.pdf

 

Measurement of Socioeconomic Disadvantage

Medicare Beneficiaries In Disadvantaged Neighborhoods Increased Telemedicine Use During The COVID-19 Pandemic.pdf

 

Medicare and Medicaid Policy

In Medicaid Managed Care Networks, Care Is Highly Concentrated Among A Small Percentage Of Physicians.pdf

 

Precision Gerontology and Heterogeneity in Aging

Toward precision interventions and metrics of inflammaging.pdf

Function Begets Function and Resilience in Old Age: Is Precision Gerontology Possible?.pdf

Heterogeneity in Healthy Aging.pdf

Heterogeneity of Aging: Individual Risk Factors, Mechanisms, Patient Priorities, and Outcomes.pdf

Heterogeneous Long-Term Trajectories of Dependency in Older Adults: The PAQUID Cohort, a Population-Based Study over 22 years.pdf

Increased molecular damage and heterogeneity as the basis of aging.pdf

Individual Heterogeneity in the Probability of Hospitalization, Skilled Nursing Facility Admission, and Mortality.pdf

The heterogeneous health state profiles of high-risk healthcare utilizers and their longitudinal hospital readmission and mortality patterns.pdf

 

Precision Medicine and Care of Older Adults

Facing multimorbidity in the precision medicine era.pdf

From precision medicine to precision care: Choosing and using precision medicine in the context of multimorbidity.pdf

 

Precision Science and Recruitment

Principles of Precision Prevention Science for Improving Recruitment and Retention of Participants.pdf

 

Recruitment

Including Older Adults with Multiple Chronic Conditions in Research.pdf

 

Research Grant Application Guidance

Why Stating Hypotheses in Grant Applications Is Unnecessary.pdf

 

Study Design Considerations

Beyond the null: Recognizing and reporting true negative findings.pdf

Effect Size Guidelines, Sample Size Calculations, and Statistical Power in Gerontology.pdf

Mendelian Randomization - Let's Prevent Common Mistakes.pdf

Randomization, design and analysis for interdependency in aging research: no person or mouse is an island.pdf

“Target Trial Emulation” for Observational Studies — Potential and Pitfalls.pdf

Mendelian randomisation for mediation analysis: current methods and challenges for implementation.pdf

 

Translational Geroscience – Review

Geroscience A Translational Review.pdf