Mary Beth McCarthy is a research associate specializing in translational research, uniting orthopaedic surgery with laboratory science. Ms. McCarthy has been conducting research in the Department of Orthopaedic Surgery for 29 years. Her laboratory experience includes new techniques utilizing stem cells, molecular and cell biology and novel applications with biomaterials. As a laboratory manager, she enjoys working with orthopaedic surgeons and research teams in the UConn Musculoskeletal Institute. Ms. McCarthy gains special satisfaction from working on a team, and training students and residents.
Specialty
- Cell and Molecular Biology
Subspecialty
- Bone and Tendon Biology
Education
B.S., Central Connecticut State University
Major: Biology, Minor: Chemistry
Selected Publications
Intravia J, Allen DA, Durant TJ, McCarthy MB, Russell R, Beitzel K, et al. In vitro evaluation of the anti-bacterial effect of two preparations of platelet rich plasma compared with cefazolin and whole blood. Muscles, ligaments and tendons journal. 2014;4:79-84.
Durant TJ, Dyment N, McCarthy MB, Cote MP, Arciero RA, Mazzocca AD, et al. Mesenchymal stem cell response to growth factor treatment and low oxygen tension in 3-dimensional construct environment. Muscles, ligaments and tendons journal. 2014;4:46-51.
[Beitzel K, McCarthy MB, Russell RP, Apostolakos J, Cote MP, Mazzocca AD. Learning about PRP using cell-based models. Muscles, ligaments and tendons journal. 2014;4:38-45.
Beitzel K, McCarthy MB, Cote MP, Russell RP, Apostolakos J, Ramos DM, et al. Properties of biologic scaffolds and their response to mesenchymal stem cells. Arthroscopy 2014;30:289-98.
Beitzel K, Allen D, Apostolakos J, Russell RP, McCarthy MB, Gallo GJ, et al. US Definitions, Current Use, and FDA Stance on Use of Platelet-Rich Plasma in Sports Medicine. The journal of knee surgery. 2014.
Mazzocca AD, McCarthy MB, Ledgard FA, Chowaniec DM, McKinnon WJ, Jr., Delaronde S, et al. Histomorphologic changes of the long head of the biceps tendon in common shoulder pathologies. Arthroscopy 2013;29:972-81.
Mazzocca AD, McCarthy MB, Intravia J, Beitzel K, Apostolakos J, Cote MP, et al. An in vitro evaluation of the anti-inflammatory effects of platelet-rich plasma, ketorolac, and methylprednisolone. Arthroscopy 2013;29:675-83.
Beitzel K, McCarthy MB, Cote MP, Durant TJ, Chowaniec DM, Solovyova O, et al. Comparison of mesenchymal stem cells (osteoprogenitors) harvested from proximal humerus and distal femur during arthroscopic surgery. Arthroscopy 2013;29:301-8.
Beitzel K, McCarthy MB, Cote MP, Apostolakos J, Russell RP, Bradley J, et al. The effect of ketorolac tromethamine, methylprednisolone, and platelet-rich plasma on human chondrocyte and tenocyte viability. Arthroscopy 2013;29:1164-74.
Research Interests
- To utilize human tissue and examine cellular responses in order to investigate and test novel biomaterials that are biologically compatible and clinically relevant. Specifically, tendon to bone healing which can possibly be enhanced by the modification of the surface of the biomaterial.