The NIH makes the results of the research it supports and conducts available to the public enabling data reuse, increasing transparency, and the facilitation of reproducibility of research results.
While open-access data can be browsed online or downloaded without prior permission, controlled-access data can only be obtained after the requestor has been authorized and IRB approval is required for some.
Specific information about the more commonly used repositories can be found below.
The database of Genotypes and Phenotypes (dbGaP)
- The PI will:
- submit an on-line request to The National Center for Biotechnology Information (NCBI).
- email required documents to Sponsored Program Services (SPS).
- NCBI will notify the SPS Signing Official (SO) of the request.
- SPS will secure NCBI application and Data Use Certification Agreement (DUC) signature(s).
- The SO will approve the request in the NCBI system.
NIDDK Specimen and Data Repository
|The NIDDK Central Repository enables scientists to test new hypotheses without the need to collect any new data or biospecimens and provides the opportunity to pool data across several studies to increase the power of statistical analyses. In addition, most NIDDK-funded studies are collecting genetic biospecimens and carrying out high-throughput genotyping making it possible for other scientists to use Central Repository resources to match genotypes to phenotypes and to perform informative genetic analyses.
|Data Access is Controlled:
Summary level data is open.
National Institute of Mental Health Data Archive (NDA)
|The National Institute of Mental Health Data Archive (NDA) makes available human subjects data collected from hundreds of research projects across many scientific domains. NDA provides infrastructure for sharing research data, tools, methods, and analyses enabling collaborative science and discovery. De-identified human subjects’ data, harmonized to a common standard, are available to qualified researchers. Summary data are available to all.
|Data Access is Mixed.
|NDA access portal