Postdoctoral Fellow Positions
Postdoctoral positions in the integrative structural biology of cancer and immunity
Posted: April 1, 2024
The position. The Page Laboratory at the University of Connecticut Health Center has an immediate opening for up to two postdoctoral candidates to study eukaryotic signaling enzymes, with a focus on the function of phosphatases that form large signaling complexes and phosphatase drug/inhibitor development. We use integrative structural and cell biology to tackle research problems in cancer, development and the immune system. All studies combine cryo-EM, NMR and/or X-ray crystallography with biochemical and cellular experiments, allowing postdocs to augment their training in cutting edge new techniques.
Recent high impact publications can be found here (Nature: https://www.nature.com/articles/s41586-023-06870-3, Nature communications: https://www.nature.com/articles/s41467-023-37372-5, among others, https://publicationslist.org/rebecca.page).
Applicants. Motivated applicants with strong backgrounds in biochemical and cell biology methods, and especially eukaryotic protein expression and/or CryoEM and protein crystallization, are encouraged to apply. PhD is required.
Laboratory alumni are highly successful, with either their own academic faculty positions at tier 1 research institutions (i.e., Vanderbilt University, Dartmouth University), are directors/chief scientists in big pharma and biotech startups, named prestigious public policy fellow, among others.
The laboratory. The Page laboratory is housed in a newly renovated ~250,000 sq. ft. research laboratory in Farmington, CT. The laboratories are open-lab-space facilities and allow close interaction with the adjunct structural biology and molecular/cell biology groups at UConn Health. The Page laboratory is equipped with all necessary infrastructure to produce (E. coli, mammalian, insect), purify and analyze protein and protein complexes (ITC, SPR etc.) and crystallization robotics for crystal production (Art Robbins Gryphon LCP nano-liter crystallization robot; Art Robbins CrysCam) as well as all needed equipment for cryo-EM sample preparation and data evaluation.
Facilities. UCHC facilities include a Bruker Venture D8 system (IμS Diamond source) with a Photon III M14 detector and cold stream is available for crystal screening and data collection for in-house data collection, synchrotron access at NSLS-II, SSRL, Diamond and high-field NMRs (Bruker Avance Neo 600 MHz and 800 MHz NMR spectrometers). Cryo-EM instrument includes a TFS Vitrobot IV and a TFS Tundra/Falcon C) that allows for rapid screening of auto-grid/clipped samples of sample conditions. Access to Krios instruments for data collection is readily available.
UCHC. UCHC has a welcoming, collaborative and vibrant environment for structural, biochemical and translational research. Farmington, CT, is located in New England between Boston (90 min.) and New York City (90 min).
Starting date, salary and project details are commensurate with experience, competitive and negotiable.
Please e-mail a Cover Letter and CV to Rebecca Page (rpage@uchc.edu).
Postdoctoral Position in Translational Cancer Immunology and Biology
Posted: February 7, 2024
We are seeking a highly motivated, self-sufficient postdoctoral fellows to work on NIH-funded innovative cancer research projects. An experience in immunology or molecular biology and animal work is required. The fellow will work with a multidisciplinary team of investigators and clinician scientists within a translational cancer research. Major focuses of the research will be on mechanistic identification of critical extrinsic and intrinsic factors associated with liver cancer, non-alcoholic fatty liver disease, and pancreatic cancer. The findings are leveraged to develop effective cellular and molecularly targeted therapy and immunotherapy as well as diagnosis toward translation into clinical application. Candidates must be scientifically curious, intellectually committed, and capable of working independently. Strong communication and writing skills are essential to develop and execute independent hypothesis-driven cancer research. This position will be an excellent learning opportunity for someone interested in a future translational biomedical research, cancer biology, and immunology or medical career.
To apply, please submit your curriculum vitae, a description of previous research, career interests, research accomplishments and three references to Allyson Moffo (amoffo@uchc.edu) and Dr. Kevin Staveley-O’Carroll (ksoc@uchc.edu).
Postdoctoral Position in Sarcomere Research
Posted: January 9, 2024
The Hinson lab is seeking an independent, highly motivated PhD-level scientist to join our trans-continental collaborative group funded by the Human Frontiers Science Program (HFSP). The overarching goal of this project is to leverage human pluripotent stem cell technology and advanced structural biology methods to define mechanisms and rules of sarcomere assembly and function. The ideal candidate would have a strong background in cell and molecular biology particularly in stem cell differentiation, advanced imaging and protein-protein interaction studies. As part of the group, this talented individual would have access to a world-class consortium of scientists across pluripotent stem cell biology, 3-dimensional organoids/microtissue assays, super resolution microscopy, and structural biology. The Hinson lab at the Jackson Laboratory for Genomic Medicine and UConn Health utilizes pluripotent stem cell biology, tissue engineering, genome editing, and multi-omics assays to study mechanisms of inherited heart failure and other muscle disorders. To apply please send a letter of interest and updated CV to travis.hinson@jax.org
Postdoctoral Position in Nephrology
Posted: January 2, 2024
A full-time postdoctoral position is available in a NIH-funded laboratory in the Division of Nephrology of the Department of Medicine at the University of Connecticut School of Medicine to investigate molecular and cellular mechanisms of kidney inflammation and fibrosis. The ideal candidate will be expected to design and perform experiments, and prepare and publish manuscripts under the direction of the Principal Investigator. The candidate will work with animal models relevant to human kidney diseases and use advanced scientific techniques including flow cytometry, confocal microscope, single cell transcriptome analysis, RNA-seq, and ChIP-PCR assay. Candidates must have a PhD or MD/PhD degree in biological science or a related field and strong verbal and written communication skills. Experience with molecular and cellular biology techniques is necessary, and experience with small animal models is preferred, but not required. We offer a competitive salary and full benefits. Farmington area is one of the best places to live. Interested applicants, please email a cover letter, curriculum vitae, and names of three references to Dr. Yanlin Wang (yanlwang@uchc.edu).
The University of Connecticut Health Center is an affirmative action employer, in addition to an EEO and M/F/V/PWD/PV employer.
Postdoctoral Position in Psychiatry
Posted: December 29, 2023
The UConn Health Department of Psychiatry is hiring a 2+ year full-time postdoctoral research scholar to join the Family Adversity & Resilience Research Program led by Drs. Damion Grasso, Margaret Briggs-Gowan, and Carolyn Greene. Ample opportunities for research productivity on several NIH grants and accrual of clinical assessment and psychotherapy hours with diverse patient populations.
The successful candidate will participate in combined clinical and research activities that include delivery of psychotherapy, clinical evaluations, facilitating laboratory paradigms using psychophysiological and observational methodologies, data analysis, manuscript preparation, and mentoring student interns. Start date is flexible and salary negotiable. UConn Health is a vital place for a career in research and many postdocs have successfully transitioned to faculty. The ideal candidate will have earned a doctoral degree in clinical psychology by the fellowship start date (APA accredited), have training in cognitive-behavioral interventions, be proficient in statistical methods, and have a strong track record of scholarly contributions.
Please see additional detail, including how to apply, in the linked posting
Postdoctoral Positions in Bone or Skin Research
Posted: December 6, 2023
Two postdoctoral positions are available in NIH funded laboratories with interest in elucidating pathogenic mechanisms of rare genetic bone disorders and mechanisms of wound healing disorders, specifically keloid formation.
Candidates must have PhD, MD/PhD, or MD or equivalent and must be highly motivated.
Position 1: The successful applicant will have strong background in SKIN RESEARCH, wound healing, fibrosis or inflammatory disorders with technical expertise in induced pluripotent stem cells (iPSCs), immunology, cell biology or signal transduction.
Position 2: The successful applicant will have strong background in BONE RESEARCH with technical expertise in molecular biology, cell biology, stem cell biology or signal transduction.
Our newly renovated laboratory is embedded in the Center for Regenerative Medicine and Skeletal Development at University of Connecticut Health within a vibrant research environment.
Candidates must be innovative, enthusiastic and have a solid technical background in at least one of these areas: molecular biology, cell biology, stem cell biology or signal transduction. The successful applicant must be motivated and capable of engaging in other areas of expertise as required by the project. The dynamics of this research project requires the ability for multitasking, to work independently as well as collaboratively with other lab members and external collaborators.
Please send CV, statement of research interests, research accomplishments, and contact information for 3 references to:
Ernst Reichenberger, PhD or I-Ping Chen, D.D.S, Ph.D.
University of Connecticut Health
Center for Regenerative Medicine and Skeletal Development
263 Farmington Avenue
Farmington, CT 06030-3705
email: reichenberger@uchc.edu
Tel: 860-679-2062
email: ipchen@uchc.edu
Tel: 860-679-1030
visit us at: https://health.uconn.edu/reichenberger-lab/
The University of Connecticut Health Center is an affirmative action employer, in addition to an EEO and M/F/V/PWD/PV employer.
Postdoctoral Positions Available in Department of Medicine and Orthopaedics
Posted: August 28, 2023
The main research focus of Dr. Lorenzo is progenitor cell biology and understanding mechanism of osteoclastogenesis in homeostasis and inflammatory state. Studies will involve using transgenic and knockout mice in regulation of osteoclast differentiation of hematopoietic progenitor cells, their migration and function in healthy mice and during systemic inflammation or facture healing. Responsibilities will include discussion and planning of experimental designs, completion of experiments using established in vitro and in vivo models, presentation of data within institution and at international conferences and preparation of manuscripts.
Applicants must have a Ph.D., good command of the English language and good interpersonal skills. Experience in a hematopoiesis, bone or orthopedic-related field would be advantageous, but is not critical. USA citizens/permanent residents will have an opportunity to compete for a T90 training position funded by NIDCR.
The University of Connecticut Health Center is an affirmative action employer, in addition to an EEO and M/F/V/PWD/PV employer.
Please send curriculum vitae including qualifications, bibliography, summary of past accomplishments, and names of three references to:
Joseph Lorenzo, M.D.
Professor of Medicine and Orthopaedics
UConn Health
263 Farmington Avenue
Farmington, CT 06030-4037
Phone: (860) 679-8199
Fax: (860) 679-2109
Email: jlorenzo@uchc.edu
Sanja Novak, PhD
Center for Regenerative Medicine and Skeletal Development
UConn Health
263 Farmington Avenue
Farmington, CT 06030-4037
Mobile phone: (860) 989-6887
email: snovak@uchc.edu
Always be sure to check the UConn Health Find Jobs page for more listings.
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All employees are subject to adherence to the State Code of Ethics which may be found at http://www.ct.gov/ethics/site/default.asp.
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