Clinical Trials and Projects

Clinical Trials

ART Adherence and Secondary Prevention of HIV
The purposes of this study are to evaluate the efficacy of a cell phone reminder intervention, with and without contingency management, on ART adherence.

IRB Number: 12-205-2 (Petry)

Interactive Voice Response Technology to Mobilize Contingency Management for Smoking Cessation
The goal of this project is to examine the effectiveness of using interactive voice response technology to remotely conduct contingency management and expired carbon monoxide testing procedures.

IRB Number: 11-132-2 (Alessi)

Contingency Management for Smoking Cessation in the Homeless
This project evaluates the addition of contingency management to standard treatment to improve smoking outcomes in homeless smokers.

IRB Number: 12-186-2 (Rash)

Prize Contingency Management for Cocaine-Dependent Methadone Patients
This study varies probabilities of winning prizes and number of prize categories to identify the most efficacious contingency management approach. It is conducted with cocaine-using methadone patients, a group with significant HIV risk, as contingency management may be cost-effective in this population.

IRB Number: 110-256-2 (Alessi)

Exercise and Cognition Supplement (PI: Petry/Godfry)
The purpose of this study is to examine short- and long-term effects of a low-to-moderate-intensity exercise program on cognitive function.

IRB Number: 12-016-2 (Petry)

Healthy Activities for Prize Incentives
The purpose of this study is to evaluate a contingency management approach for increasing adherence to an exercise regimen in HIV positive patients.

IRB Number: 08-251S-2 (Petry)

Reinforcing Exercise in Substance Abusers
The purpose of this study is to evaluate the efficacy of a contingency management intervention that reinforces adherence with exercise in reducing drug use.

IRB Number: 10-010S-2 (Petry)

A SMART Design for Attendance-based Prize Contingency Management (Yale Psychotherapy Development Research Center; PI: Carroll)
The purpose of this study is to evaluate attendance-based versus abstinence-based reinforcement procedures for the treatment of cocaine dependence.

IRB Number: 09-053-2 (Petry)

Contingency Management Treatment Duration (Alcohol Research Center; PI: Hesselbrock)
Systematic exploration of the alcohol dependence syndrome, its etiology, patterning and treatment.

IRB Number: 08-053-2 (Petry)

A Behavioral Intervention for Reducing Obesity (UConn Health/Storrs and Regional Campus Incentive Grant)
The purpose of this study is to evaluate the efficacy of contingency management in reducing obesity and improving indicators of cardiovascular health in obese individuals.

IRB Number: 09-128-1 (Petry)

Contingency Management for Promoting Weight Loss in University Students (WeLcome)
The primary aim of this study is to evaluate the efficacy of a contingency management intervention for promoting weight loss and to evaluate the efficacy of contingency management in increasing retention in the weight loss program, enhancing physical activity level and improving nutrition.

IRB Number (Storrs): H0967 (Petry)

Contingency Management for Initiating Smoking Abstinence
This study will examine whether contingency management increases short- and long-term smoking cessation outcomes, and reduces blood pressure, when applied in conjunction with varenicline in hypertensive smokers.

IRB Number: 08-218-3 (White)

Contingency Management for Marijuana Dependence
This is an active component study of a new treatment for marijuana dependence. Interactive voice response technology is used to enhance adherence to treatment activities. Contingency management is used to increase rate of abstinence or rate of completion of treatment assignments.

IRB Number: 06-557-1 (Litt)

Contingency Management and Pharmacotherapy for Smoking Cessation
The purpose of this pilot study is to evaluate the effects of adding contingency management to a medication for smoking cessation to determine if contingency management improves smoking cessation rates.

IRB Number: 04-128-1 (Alessi)

Motivational Interventions for Exercise in Hazardous Drinking College Students
The purpose of this study is to investigate exercise promotion as an intervention in sedentary hazardous drinking college students.

IRB Number: H09-043UCHC (Weinstock)

Contingency Management To Promote Weight Loss In Low Income Adults (Ethel Donaghue Center for Translating Research into Practice and Policy)
The purpose of this study is to evaluate the feasibility and provide preliminary evidence for efficacy of a contingency management intervention to promote weight loss in overweight and obese low income adults.

IRB Number: 09-108-2 (Barry)

Projects

Recovery Enhancement with Awards Research Dissemination (REWARD) Center
This Center grant is designed to cross coordinate administrative structure, data management and training and supervision in contingency management treatment trials.

P30-DA023918 (Petry)

Improving Antihypertension Medication Adherence (Pilot)
The purpose of this study is to evaluate effects of cell phone-based monitoring plus incentives on blood pressure medication adherence and blood pressure.

IRB Number: 11-080-3 (Petry)

Remote Monitoring and Contingency Management Reinforcement for Alcohol Abstinence (Pilot)
The purpose of this study is to determine the feasibility and efficacy of using cell phone technology to objectively and frequently monitor alcohol use and reinforce abstinence in individuals' natural environment.

IRB Number: 11-058-1 (Alessi)

Contingency Management for Persons with Severe Mental Illness (Pilot)
The purpose of this study is to examine effects of contingency management for cocaine abstinence in patients with severe and persistence mental illness receiving psychiatric care at a large community-based mental health program.

IRB Number: 12-070-3 (Petry)

Substance Use and Fitness: A Pilot Study of Contingency Management in Older Adults
The purpose of this pilot is to estimate the effect size of a contingency management procedure that reinforces walking at rates consistent with the ACSM recommendations of 10,000 or more steps per day in older adults.

IRB Number: 11-040-2 (Petry)

Extending Contingency Management's Benefits with Progressively Increasing Variable Interval Prize Reinforcement (Pilot)
The purpose of this project is to determine if introducing a modified variable interval schedule of prize reinforcement that progressively increases the interval between reinforcement opportunities can extend beneficial effects of contingency management following three weeks of standard prize contingency management.

IRB Number: 10-249.1 (Petry)