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EMPLOYMENT OPPORTUNITY

 

Position Title: Post-Doc Research Scientist

Field(s) of Specialization: Molecular biology, Atherosclerosis, Metabolism, Functional genomics, Chromatin capture, RNA-Seq

Description: The Rodriguez Lab group seeks a post-doctoral research scientist. The successful candidate ideally should have advanced skills in functional genomics and molecular biology in pursuit of the genetic and molecular basis of human heart disease. Experience in genetic discovery (e.g., Chromatin capture, RNA-seq, ChIP-seq etc.) and related functional mouse model systems are a must. He/she will focus on genomics of immune checkpoint inhibition and atherosclerosis and the NIH-sponsored project will involve cutting-edge single cell technology, functional genomics and transcriptomics, gene editing, chromatin capture as well as rodent modeling.

Applicant MUST meet this minimum qualifications to be considered an applicant:

Requires a PhD, MD, or MD PhD or equivalent doctoral training. Experience in functional genomics, molecular biology including cell systems and mouse models of human cardiometabolic disease.

Applicants meeting these qualifications will be considered stronger candidates:

Experience with analysis and bioinformatics of genome wide data (SNP-GWAS, exome/whole genome data RNAseq, ChIPseq); experience with mouse models and in vivo phenotyping of vascular or metabolic traits.

Applicants that meet the above-mentioned requirements, please contact Dr. Annabelle Rodriguez-Oquendo for more information.

News

Publications

Caromile LA, Dortche K, Rahman MM, Grant CL, Stoddard C, Ferrer FA, Shapiro LH. PSMA redirects cell survival signaling from the MAPK to the PI3K-AKT pathways to promote the progression of prostate cancer. Sci Signal. 2017 Mar 14;10(470).pii: eaag3326. doi: 10.1126/scisignal.aag3326. PubMed PMID: 28292957. Full text.

Golden D, Kolmakova A, Sura S, Vella AT, Manichaikul A, Wang XQ, Bielinski SJ, Taylor KD, Chen YI, Rich SS, Rodriguez A. Lymphocyte activation gene 3 and coronary artery disease. JCI Insight. 2016 Oct 20;1(17):e88628. PubMed PMID: 27777974.

Qendro V, Bugos GA, Lundgren DH, Glynn J, Han MH, Han DK. Integrative proteomics, genomics, and translational immunology approaches reveal mutated forms of Proteolipid Protein 1 (PLP1) and mutant-specific immune response in multiple sclerosis. Proteomics. 2017 Mar;17(6). doi: 10.1002/pmic.201600322. PubMed PMID: 28191734.

Kopsiaftis S, Hegde P, Taylor JA 3rd, Claffey KP. AMPKα Is Suppressed in Bladder Cancer through Macrophage-Mediated Mechanisms. Transl Oncol. 2016 Dec;9(6):606-616. doi: 10.1016/j.tranon.2016.07.007. PubMed PMID: 27916296.

Kopsiaftis S, Sullivan KL, Garg I, Taylor JA 3rd, Claffey KP. AMPKα2 Regulates Bladder Cancer Growth through SKP2-Mediated Degradation of p27. Mol Cancer Res. 2016 Dec;14(12):1182-1194. Epub 2016 Sep 16. PubMed PMID: 27638620.