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  • Our Center's Director, Dr. Linda H. Shapiro, has been elected to the NAVBO Council -- Congratulations!



Devarakonda CV, Pereira FE, Smith JD, Shapiro LH, Ghosh M. CD13 deficiency leads to increased oxidative stress and larger atherosclerotic lesions. Atherosclerosis. In Press Accepted Manuscript Published online: June 13, 2019 DOI:10.1016/j.atherosclerosis.2019.06.901

Ghosh M, Lo R, Ivic I, Aguilera B, Qendro V, Devarakonda C, Shapiro LH. CD13 tethers the IQGAP1-ARF6-EFA6 complex to the plasma membrane to promote ARF6 activation, β1 integrin recycling, and cell migration. Sci Signal. 2019 Apr 30;12(579). pii: eaav5938. doi: 10.1126/scisignal.aav5938.

Dimitrova E, Caromile LA, Laubenbacher R, Shapiro LH. The innate immune response to ischemic injury: a multiscale modeling perspective. BMC Syst Biol. 2018 Apr 10;12(1):50. doi: 10.1186/s12918-018-0580-z.

Ghosh M, Thangada S, Dasgupta O, Khanna KM, Yamase HT, Kashgarian M, Hla T, Shapiro LH, Ferrer FA. Cell-intrinsic sphingosine kinase 2 promotes macrophage polarization and renal inflammation in response to unilateral ureteral obstruction. PLoS One. 2018 Mar 8;13(3):e0194053. doi: 10.1371/journal.pone.0194053.eCollection 2018.

Caromile LA, Dortche K, Rahman MM, Grant CL, Stoddard C, Ferrer FA, Shapiro LH. PSMA redirects cell survival signaling from the MAPK to the PI3K-AKT pathways to promote the progression of prostate cancer. Sci Signal. 2017 Mar 14;10(470).pii: eaag3326. doi: 10.1126/scisignal.aag3326. PubMed PMID: 28292957. Full text.

Golden D, Kolmakova A, Sura S, Vella AT, Manichaikul A, Wang XQ, Bielinski SJ, Taylor KD, Chen YI, Rich SS, Rodriguez A. Lymphocyte activation gene 3 and coronary artery disease. JCI Insight. 2016 Oct 20;1(17):e88628. PubMed PMID: 27777974.

Qendro V, Bugos GA, Lundgren DH, Glynn J, Han MH, Han DK. Integrative proteomics, genomics, and translational immunology approaches reveal mutated forms of Proteolipid Protein 1 (PLP1) and mutant-specific immune response in multiple sclerosis. Proteomics. 2017 Mar;17(6). doi: 10.1002/pmic.201600322. PubMed PMID: 28191734.

Kopsiaftis S, Hegde P, Taylor JA 3rd, Claffey KP. AMPKα Is Suppressed in Bladder Cancer through Macrophage-Mediated Mechanisms. Transl Oncol. 2016 Dec;9(6):606-616. doi: 10.1016/j.tranon.2016.07.007. PubMed PMID: 27916296.

Kopsiaftis S, Sullivan KL, Garg I, Taylor JA 3rd, Claffey KP. AMPKα2 Regulates Bladder Cancer Growth through SKP2-Mediated Degradation of p27. Mol Cancer Res. 2016 Dec;14(12):1182-1194. Epub 2016 Sep 16. PubMed PMID: 27638620.