Our Center's Director, Dr. Linda H. Shapiro, has been elected to the NAVBO Council -- Congratulations!
macrophages co-cultured with splicing-mutated endothelial cells
alternatively spliced extracellular matrix beneath arterial endothelium
brain vasculature in vivo by multi-photon Imaging
News
Publications
Devarakonda CV, Pereira FE, Smith JD, Shapiro LH, Ghosh M. CD13 deficiency leads to increased oxidative stress and larger atherosclerotic lesions. Atherosclerosis. In Press Accepted Manuscript Published online: June 13, 2019 DOI:10.1016/j.atherosclerosis.2019.06.901
Ghosh M, Lo R, Ivic I, Aguilera B, Qendro V, Devarakonda C, Shapiro LH. CD13 tethers the IQGAP1-ARF6-EFA6 complex to the plasma membrane to promote ARF6 activation, β1 integrin recycling, and cell migration. Sci Signal. 2019 Apr 30;12(579). pii: eaav5938. doi: 10.1126/scisignal.aav5938.
Dimitrova E, Caromile LA, Laubenbacher R, Shapiro LH. The innate immune response to ischemic injury: a multiscale modeling perspective. BMC Syst Biol. 2018 Apr 10;12(1):50. doi: 10.1186/s12918-018-0580-z.
Ghosh M, Thangada S, Dasgupta O, Khanna KM, Yamase HT, Kashgarian M, Hla T, Shapiro LH, Ferrer FA. Cell-intrinsic sphingosine kinase 2 promotes macrophage polarization and renal inflammation in response to unilateral ureteral obstruction. PLoS One. 2018 Mar 8;13(3):e0194053. doi: 10.1371/journal.pone.0194053.eCollection 2018.
Caromile LA, Dortche K, Rahman MM, Grant CL, Stoddard C, Ferrer FA, Shapiro LH. PSMA redirects cell survival signaling from the MAPK to the PI3K-AKT pathways to promote the progression of prostate cancer. Sci Signal. 2017 Mar 14;10(470).pii: eaag3326. doi: 10.1126/scisignal.aag3326. PubMed PMID: 28292957. Full text.
Golden D, Kolmakova A, Sura S, Vella AT, Manichaikul A, Wang XQ, Bielinski SJ, Taylor KD, Chen YI, Rich SS, Rodriguez A. Lymphocyte activation gene 3 and coronary artery disease. JCI Insight. 2016 Oct 20;1(17):e88628. PubMed PMID: 27777974.
Qendro V, Bugos GA, Lundgren DH, Glynn J, Han MH, Han DK. Integrative proteomics, genomics, and translational immunology approaches reveal mutated forms of Proteolipid Protein 1 (PLP1) and mutant-specific immune response in multiple sclerosis. Proteomics. 2017 Mar;17(6). doi: 10.1002/pmic.201600322. PubMed PMID: 28191734.
Kopsiaftis S, Hegde P, Taylor JA 3rd, Claffey KP. AMPKα Is Suppressed in Bladder Cancer through Macrophage-Mediated Mechanisms. Transl Oncol. 2016 Dec;9(6):606-616. doi: 10.1016/j.tranon.2016.07.007. PubMed PMID: 27916296.
Kopsiaftis S, Sullivan KL, Garg I, Taylor JA 3rd, Claffey KP. AMPKα2 Regulates Bladder Cancer Growth through SKP2-Mediated Degradation of p27. Mol Cancer Res. 2016 Dec;14(12):1182-1194. Epub 2016 Sep 16. PubMed PMID: 27638620.