Biomedical Science Faculty

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

JAX_icon=The Jackson Laboratory for Genomic Medicine affliated faculty

A


Adam J. Adler, Professor of Immunology, Ph.D., Columbia University. Our lab studies mechanisms of T cell tolerization to peripheral self-antigens, as well as the relationship between tolerance and tumor immunity.

Hector Leo Aguila, Associate Professor of Immunology, Ph.D., Albert Einstein College of Medicine. Hematopoiesis and bone marrow microenvironment; lymphoid cell development; stem cell biology.

Olga Anczuków-Camarda, JAX_icon Assistant Professor of Genetics and Genome Sciences, Ph.D., Université Claude Bernard Lyon. Characterizing the role of alternative-splicing misregulation in breast and ovarian cancer by using 3D cell culture and PDX models.

Srdjan Antic, Associate Professor of Neuroscience, M.D., Belgrade University. Prefrontal and somatosensory cortex; pyramidal neurons; synaptic transmission; excitatory neurotransmitters; the role of dendrites in synaptic integration; and dopaminergic modulation of dendritic excitability.

Andrew Arnold, Professor of Medicine and Genetics and Genome Sciences, Murray-Heilig Chair in Molecular Medicine, Director, Center for Molecular Medicine, M.D., Harvard University. Pathogenesis of parathyroid and other endocrine tumors, and role of the cyclin D1 oncogene in neoplasia, including breast cancer.

B


Jacques Banchereau, JAX_icon Professor of Immunology, Ph.D., University of Paris. Systems Biology (“Omics”) of the human immune response in health and diseases.

Rashmi Bansal, Professor of Neuroscience, Ph.D., Central Drug Research Institute. Multiple Sclerosis, signaling mechanisms that regulate development, myelination, demyelination and remyelination in transgenic mouse models and in tissue culture.

Elisa Barbarese, Professor of Neuroscience, Ph.D., McGill University. Cellular and molecular biology of glia and neurons and their role in multiple sclerosis and autism.

Kyle Baumbauer, Assistant Professor of Neuroscience, Ph.D., Kent State University. Neurons responsible for transmitting sensory information to the central nervous system; the primary afferents.

Dashzeveg Bayarsaihan, Associate Professor of Reconstructive Sciences, Ph.D., Wesleyan University. Research interests are complex human disorders using stem cell technology, functional genomics and animal models to understand chromatin architecture and epigenetic modifications.

Leslie R. Bernstein, Professor of Neuroscience, Ph.D., University of Illinois. Behavioral neuroscience: psychoacoustics.

Irina Bezsonova, Assistant Professor of Molecular Biology and Biophysics, Ph.D., University of Toronto. Structural and biochemical characterization of proteins and protein complexes of p53 pathway, especially, proteins responsible for maintenance of an appropriate level of p53 in the cell.

Michael Blinov, Assistant Professor of Genetics and Genome Sciences, Ph.D., Weizmann Institute of Science. Computational Biology: Modeling of signal transcription systems and protein-DNA interactions. Bioinformatics: Data mining and visualization. Developing software tools and mathematical methods for rule-based modeling of signal transduction systems.

Stefan Brocke, Associate Professor of Cell Biology, M.D., Freie Universistaet Berlin School of Medicine.  Cellular and molecular mechanisms of brain injury in inflammatory and inflammation-associated disorders of the central nervous system.

C


Melissa Caimano, Assistant Professor of Medicine, Ph.D., University of Alabama at Birmingham. The regulatory pathways and molecular mechanisms underlying mammalian host adaptation and maintenance of Borrelia burgdorferi within its natural enzootic cycle.

Ernesto Canalis,Professor of Orthopaedic Surgery and Medicine, M.D., Universidad Peruana Cayetano Heredia. The role of growth factors and their antagonists in skeletal function, such as osteoblast cell fate and function. The role of Notch and Nuclear factor of activated T cells (NFAT) in osteoblasts in vivo and in vitro, and in disease models for Hajdu Cheney Syndrome and Lateral Meningocele Syndrome.

Gordon G. Carmichael, Professor of Genetics and Genome Sciences, Ph.D., Harvard University. Regulation of gene expression in eukaryotes.

Leslie Caromile, Assistant Professor of Cell Biology; Ph.D. University of Washington.

John H. Carson, Professor of Molecular Biology and Biophysics, Ph.D., Massachusetts Institute of Technology. RNA transport in cells of the nervous system.

Linda Cauley, Assistant Professor of Immunology, Ph.D., Oxford University, England. T-cell memory and respiratory virus infections.

Stormy J. Chamberlain, Assistant Professor of Genetics and Genome Sciences. Ph.D., University of Florida. Human induced pluripotent stem (iPS) cell models to study 15q11-q13 imprinting disorders.

I-Ping Chen, Assistant Professor, Oral Health and Diagnostic Sciences, D.D.S., Ph.D., UConn Health. Generation of induced pluripotent stem (iPS) cells from craniometaphyseal dysplasia (CMD) patients and investigation of osteoclast biology in the human stem cell system as well as in CMD mouse models.

Albert Cheng, JAX_icon Assistant Professor of Genetics and Genome Sciences, Ph.D., Massachusetts Institute of Technology. Engineering and appling artificial DNA and RNA binding proteins to study the genome, epigenome, and transcriptome.

Jeffrey Chuang, JAX_icon Associate Professor, Genetics and Genome Sciences, Ph.D., Massachusetts Institute of Technology. Computational biology and bioinformatics; genomics, gene regulation, molecular evolution, and metabolomics. Post-transcriptional regulation and cancer genomics.

Kevin Claffey, Professor of Cell Biology, Ph.D., Boston University School of Medicine. Angiogenesis in cancer progression and metastasis; vascular endothelial growth factor (VEGF) expression; hypoxia-mediated gene regulation.

Robert B. Clark, Professor of Immunology, M.D., Stanford. Autoimmunity; immune regulation; regulatory T cells.

Justin Cotney, Assistant Professor of Genetics and Genome Sciences, Ph.D. Emory University. Determining how gene regulatory elements, namely enhancers, control gene expression during mammalian development.

Ann Cowan, Professor of Molecular Biology and Biophysics; Deputy Director, Center for Biomedical Imaging Technology; Ph.D., University of Colorado. Research encompassing several areas of mammalian sperm development.

Stephen J. Crocker, Associate Professor of Neuroscience, Ph.D., University of Ottawa. Stem cells; glia; metalloproteinases; cytokines; development; pathology; tissue culture.

Jonathan Covault, Professor of Psychiatry, M.D., Ph.D., University of Iowa.  Genetic correlates of alcohol use disorders and the role of neuroactive steroids in the effects of alcohol.

D


Soheil (Sam) Dadras, Associate Professor of Dermatology, and Genetics and Genome Sciences, M.D./Ph.D. Northwestern University. Discovery of small RNAs (including microRNA) as novel biomarkers in human melanoma progression and metastasis using next generation sequencing.

Asis K. Das, Professor of Molecular Biology and Biophysics, Ph.D., University of Calcutta. Genetics, genomics and mechanisms of bacterial adaptive response; genetic control of bacteriophage lysogeny and lysis; and non-coding RNAs in prokaryotic development.

Caroline N. Dealy, Associate Professor of Reconstructive Sciences, Ph.D., University of Connecticut. Regulation of articular cartilage differentiation and homeostasis by matrix and growth factors; genetic control of skeletal development and regeneration; stem cells for repair or regeneration of cartilage or limb tissue; stem cells as models for cartilage disease.

Anne Delany, Associate Professor of Medicine. Ph.D., Dartmouth College. Regulation of osteoblast and osteoclast gene expression by microRNAs; Molecular mechanisms controlling bone remodeling.

Patricia I. Diaz, Associate Professor of Oral Health and Diagnostic Sciences, Ph.D., The University of Adelaide. Inter-species interactions in oral microbial communities that determine oral biofilm formation. Shifts in the oral microbiome composition associated with oral diseases such as mucositis during cancer chemotherapy and periodontal diseases. Interaction of oral microbial communities with the host.

Kimberly Dodge-Kafka, Associate Professor of Cell Biology/Center for Cardiology and Cardiovascular Research, Ph.D., University of Texas Health Science Center-Houston. Molecular mechanism of signaling pathways in the heart.

Anna Dongari-Bagtzoglou, Professor, Department of Oral Health and Diagnostic Sciences, D.D.S., Aristotle University, Greece, Ph.D., University of Texas, San Antonio. Pathogenesis of oral opportunistic infections in the immunocompromised host. Regulation of oral mucosal inflammation in response to bacterial or fungal infection. Innate immune factors which limit oral mucosal infection and invasion.

David I. Dorsky, Associate Professor of Medicine, M.D., Ph.D., Harvard. Anti-HIV and anti-herpes virus drug mechanisms, herpesviral DNA polymerases, gene transfer strategies applied to bioengineering and studies of antigen presentation.

E


Betty Eipper, Professor of Molecular Biology and Biophysics, Cell Biology, Neuroscience, Ph.D., Harvard University. Biosynthesis and secretion of peptides by neurons and endocrine cells.

Paul Epstein, Associate Professor of Cell Biology; Ph.D., Albert Einstein College of Medicine. Targeting the cAMP signaling pathway for treatment of leukemia and breast cancer.

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Alan Fein, Professor of Cell Biology, Ph.D., Johns Hopkins. Molecular basis of visual excitation and adaptation.

Guo-Hua Fong, Professor of Cell Biology, Ph.D., University of Illinois. Developmental biology of the vascular system, VEGF-A receptor signal transduction, embryonic stem cells and gene knock-out in mice.

Marion E. Frank, Professor of Oral Health and Diagnostic Sciences; Director, Center for Neurosciences, Ph.D., Brown University. Gustatory neurophysiology, neuroanatomy, behavior and disorders; processing of chemosensory information by the nervous system; clinical testing of oral chemosensory function in humans.

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Mallika Ghosh, Assistant Professor of Cell Biology; Ph.D., Indian Institute of Chemical Biology.

A. Jon Goldberg, Professor of Reconstructive Sciences, Ph.D., University of Michigan. Biomaterials, with studies involving structure-property relationships, development of novel systems, clinical evaluations and surface analysis.

Brenton R. Graveley, Professor of Genetics and Genome Sciences, Ph.D., University of Vermont. Regulation of alternative pre-mRNA splicing.

Michael Gryk, Associate Professor of Molecular Biology and Biophysics, Ph.D., Stanford University. Three dimensional structure and function of proteins involved in DNA repair.

Arthur Günzl, Professor of Genetics and Genome Sciences and Center for Microbial Pathogenesis, Ph.D., University of Tübingen. Transcription and Antigenic Variation in the mammalian parasite Trypanosoma brucei.

Rosaria Guzzo, Assistant Professor, Ph.D. University of Ottowa. Identification of key epigenetic mechanisms that modulate the cartilage-forming potential of human iPS cells.

H


David Han, Associate Professor of Cell Biology, Ph.D., Washington University. Apoptosis signaling using proteomics and mass spectrometry and bioinformatics technologies.

Marc Hansen, Professor of Medicine, Ph.D., University of Cincinnati College of Medicine. Molecular genetics of osteosarcoma and related bone diseases.

Bing Hao, Associate Professor of Molecular Biology and Biophysics, Ph.D., Ohio State University. Understanding how the cell cycle is regulated by ubiquitin-mediated proteolysis using x-ray crystallography as a primary tool.

Laura Haynes, Professor of Immunology, Ph.D., University of Rochester School of Medicine. How aging influences immune responses, especially to infectious diseases such as influenza and bacterial pneumonia. Mechanisms involved in specific age-related changes in the immune system and how these changes influence the generation of protective immunity following infection or vaccination.

Christopher Heinen, Associate Professor of Medicine, Ph.D., University of Cincinnati. Biochemical and cellular defects of the DNA mismatch repair pathway during tumorigenesis.

J. Travis Hinson, Assistant Professor of Cardiology and Genetics and Genome Sciences, M.D., Harvard University. Human iPS disease modeling of cardiovascular disorders, functional genomics, regenerative medicine related to the heart, and CRISPR/CAS9 genomewide screens in iPS-cell assays.

Jeff Hoch, Professor of Molecular Biology and Biophysics and Director of Gregory P. Mullen NMR Structural Biology Facility, Ph.D., Harvard University. Biophysical chemistry of proteins.

Marja Hurley, Professor of Medicine, M.D., University of Connecticut School of Medicine. Molecular mechanisms by which members of the fibroblast growth factor (FGFs) and fibroblast growth factor receptor (FGFR) families, (produced by osteoblasts, osteoclasts and stromal cells) regulate bone development, remodeling and disorders of bone. Fgf2 knockout and Fgf2 transgenic mice are utilized in loss and gain of function experiments to elucidate the role of FGF-2 in disorders of bone including osteoporosis.

I


Mayu Inaba-Oguro, Assistant Professor of Cell Biology, Ph.D., Kyushu University, M.D., Ehime University School of Medicine. Molecular and cellular mechanisms that regulate the asymmetric stem cell division; how niche signal is the spatially restricted with the emphasis on the novel stem cell specific structure, MT (microtubule based) -nanotubes.

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Laurinda A. Jaffe, Professor of Cell Biology, Ph.D., UCLA. The cell biology of fertilization, and the regulation of meiosis in oocytes.

Evan Jellison, Assistant Professor of Immunology, Ph.D., University of Massachusetts.

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Ivo Kalajzic, Associate Professor of Reconstructive Sciences, and Genetics and Genome Sciences, M.D., Ph.D., University of Zagreb School of Medicine, Croatia. Bone biology, differentiation of the osteoblast lineage cells.

Yusuf Khan, Assistant Professor of Orthopaedic Surgery and Chemical, Materials and Biomolecular Engineering, Ph.D., Drexel University. Strategies to synthesize scaffolds that are also capable of delivering proteins and growth factors essential for complete and adequate healing of bone defects through the use of biodegradable polymers alone and in combination with ceramic materials.

Stephen M. King, Professor of Molecular Biology and Biophysics, Ph.D., University College, London. Cell Biology, Structure and Function of Molecular Motors, Dynein biochemistry and Cell Biology, Structural Biology.

Lawrence A. Klobutcher, Professor of Molecular Biology and Biophysics, Ph.D., Yale University. DNA rearrangement in eukaryotic cells, phagocytosis.

Dmitry Korzhnev, Assistant Professor, Molecular Biology and Biophysics, Ph.D., Moscow Institute of Physics and Technology. Liquid-state nuclear magnetic resonance (NMR) studies of structure and dynamics of proteins and their assemblies; multi-protein complexes involved in DNA replication and repair; protein folding.

Barbara Kream, Professor of Medicine, and Genetics and Genome Sciences, Ph.D., Yale University. Hormonal regulation of bone remodeling.

George Kuchel, Professor of Medicine, M.D., McGill University. Molecular mechanisms of bladder muscle survival. Role of hormones, cytokines and genetic factors in geriatric disability.

Liisa T. Kuhn, Associate Professor of Reconstructive Sciences, Ph.D., University of California-Santa Barbara. Biomaterials for drug delivery and bone regeneration and repair.

Sangamesh Kumbar, Assistant Professor of Orthopaedic Surgery, Ph.D., Karnatak University. Synthesis and characterization of novel biomaterials/polymers for tissue engineering and drug delivery applications.

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Reinhard Laubenbacher, Professor of Cell Biology, Ph.D., Northwestern University. Quantitative approaches to medicine, mathematical modeling of molecular and tissue processes, bioinformatics.

Cato Laurencin, University Professor, Van Dusen Distinguished Endowed Professor of Orthopaedic Surgery, Professor of Craniofacial Sciences, Professor of Chemical and Biomedical Engineering and Materials Science, M.D., Harvard Medical School, Ph.D., Massachusetts Institute of Technology.  Regenerative Engineering using biomaterials, stem cells, physics, and developmental biology.

Sun-Kyeong Lee, Associate Professor of Medicine, Ph.D., University of Connecticut. Osteoclast biology and molecular and cellular regulation by cytokines in osteoclastogenesis.

Eric S. Levine, Professor of Neuroscience, Ph.D., Princeton University. Synaptic physiology and plasticity, roles of nerve growth factors and endogenous cannabinoids in hippocampus and cortex.

James Li,  Professor of Genetics and Genome Sciences, Ph.D., University of Texas. Mechanisms underlying normal and abnormal development of the central nervous system; stem cell biology.

Bruce Liang, Professor of Medicine, M.D., Harvard Medical School. Signal transduction, cardiac and vascular cell biology, receptors, G proteins, transgenic mice.

Alexander Lichtler, Associate Professor of Genetics and Genome Sciences, Ph.D., University of Florida. Regulation of collagen gene transcription; retrovirus vectors; role of homeobox genes in limb development.

Edison T. Liu, JAX_icon Professor of Genetics and Genome Sciences, M.D., Stanford University. President and CEO The Jackson Laboratory.

Leslie M. Loew, Professor of Cell Biology, and Computer Science and Engineering, Ph.D., Cornell. Morphological determinants of cell physiology; image-based computational models of cellular biology; synapse biophysics; new optical methods for probing living cells.

Alan G. Lurie, Professor of Oral Health and Diagnostic Sciences; Head, Division of Oral and Maxillofacial Radiology, D.D.S., UCLA, Ph.D., University of Rochester. Digital imaging analysis of dental and bone diseases.

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Xin-Ming Ma, Professor of Neuroscience, Ph.D., Beijing University School of Medicine. Synaptogenesis and spine plasticity in hippocampal neurons; estrogen hormones, cocaine, stress and synaptic plasticity.

Mark Maciejewski, Associate Professor of Molecular Biology and Biophysics, Ph.D., Ohio State University. Utilizing NMR to characterize the three dimensional structure, function and dynamics of proteins from a wide range of important biological systems.

Richard Mains, Professor of Neuroscience, Ph.D., Harvard University. Pituitary; sympathetic neurons; peptides; vesicles; enzymes; tissue culture; development.

David Martinelli, Assistant Professor of Neuroscience, Ph.D., Johns Hopkins University. Understanding the molecular logic of how synaptic adhesion proteins orchestrate synaptic formation, modification, and function, and ultimately providing an explanation for how these events influence behaviors, in particular the aberrant behaviors associated with neuropsychiatric diseases.

Brya Matthews, Assistant Professor of Reconstructive Sciences; Ph.D., University of Auckland.

Nilanjana Maulik, Professor of Surgery, Ph.D., University of Calcutta. Molecular and Cellular signaling during myocardial ischemia and reperfusion.

Peter Maye, Assistant Professor of Reconstructive Sciences, Ph.D., Wesleyan University. Isolation, characterization and differentiation of embryonic and adult skeletal stem cells down the osteogenic lineage.

Bruce J. Mayer, Professor of Genetics and Genome Sciences, Ph.D., Rockefeller University, Mechanisms of signal transduction.

Andrei Medvedev, Associate Professor of Immunology, Ph.D., Gabrichevsky Epidemiol & Microbiol Institute. How distorted control of TLR signaling underlies immune pathologies.

Lisa M. Mehlmann, Assistant Professor of Cell Biology, Ph.D., Kent State University. Cell signaling events that regulate oocyte maturation and fertilization, maintenance of oocyte meiotic arrest by G-protein coupled receptors, hormonal regulation of oocyte maturation.

Pedro Mendes, Professor, Center for Quantitative Medicine; Ph.D., University of Wales. Computational systems biology: better understanding biological systems through the use of computer models.

Mina Mina, Professor of Craniofacial Sciences, D.M.D., National University of Iran, Ph.D., University of Connecticut.  Origin, maintenance, proliferation and differentiation of adult stem cells in dental pulp.

Royce Mohan, Associate  Professor of Neuroscience, Ph.D., The Ohio State University. Chemical genetic approaches in corneal angiogenesis, fibrosis and retinal gliosis.

William A. Mohler, Associate Professor of Genetics and Genome Sciences, Ph.D., Stanford University. Developmental cell fusion; C. elegans genetics; multidimensional imaging of developmental and cell biological processes.

Ion Moraru, Professor of Cell Biology, Ph.D., Carol Davila University of Medicine. Understanding signal transduction mechanisms, in particular related to calcium and phosphoinositides.

Patrick Murphy, Assistant Professor of Cell Biology, Ph.D., University of California-San Francisco.  Unraveling the complex interplay between recruited immune cells and the endothelial lining of the vasculature in chronic inflammation, with a focus on alternative splicing and changes in the sub-endothelial matrix as critical determinants of that interaction.

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Lakshmi Nair, Associate Professor of Orthopaedic Surgery and Chemical, Materials and Biomolecular Engineering, Ph.D., SCTIMST, India. Design and development of regenerative biomaterials to favorably modulate the responses of a variety of cell types involved in tissue regeneration and repair.

Syam P. Nukavarapu, Assistant Professor of Orthopaedic Surgery, and Chemical, Materials and Biomolecular Engineering. Ph.D., Indian Institute of Science (IISc). Scaffold based bone tissue engineering.

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Julia Oh, JAX_icon Assistant Professor of Genetics and Genome Sciences, Ph.D., Stanford University. Potential of the human microbiome—the diverse bacteria, fungi, and viruses that inhabit our bodies—to deliver treatments for infectious and other diseases.

Douglas L. Oliver, Professor of Neuroscience, Ph.D., Duke University. Synaptic organization; parallel information processing in the central nervous system; Ionic currents and channel expression and their role in information processing; neurocytology, morphology, and cellular physiology of CNS sensory systems; biology of hearing and deafness.

Zhengqing Ouyang, JAX_icon Assistant Professor of Genetics and Genome Sciences, Ph.D., Stanford University. Development and application of statistical and computational methodologies in the area of regulatory genomics. Chromatin structure, lncRNA, epigenomics and epitranscriptomics, and regulatory network.

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Joel S. Pachter, Professor of Cell Biology, Ph.D., NYU. Use of laser capture microdissection for gene profiling of the neurovascular unit in health and disease.

Karolina Palucka, JAX_icon Professor of Immunology, Ph.D., Karolinska Institute. Human immunology with a focus on experimental immunotherapy.

John J. Peluso, Professor of Cell Biology, Ph.D., West Virginia University. Hormonal control of ovarian follicular growth and atresia (apoptosis); characterization of a putative membrane receptor for progesterone.

Carol C. Pilbeam, Professor of Medicine, Ph.D., Yale University. M.D., Yale School of Medicine. Mechanisms of regulation of bone formation and resorption.

Stefan Pinter, Assistant Professor of Genetics and Genomic Sciences, Ph.D., Princeton University. How chromosome topology, non-coding (nc)RNA and chromatin modifiers orchestrate gene expression.

Steven J. Potashner, Professor of Neuroscience, Ph.D., McGill University. Synaptic and transmitter biochemistry of neural connections in the auditory nervous system and their plasticity in the adult animal.

Lynn Puddington, Associate Professor of Immunology, Ph.D., Wake Forest University. Allergic asthma; neonatal immunity and tolerance; developmental immunology.

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Justin D. Radolf, Professor of Medicine and Center for Microbial Pathogenesis, M.D., University of California-San Francisco. Molecular pathogenesis and immunobiology of spirochetal infections.

T.V. Rajan, Professor of Pathology and Laboratory Medicine, Ph.D., Albert Einstein College of Medicine; M.D., All India Institute of Medical Sciences. Parasitology; filariasisl molecular immunoparasitology.

Vijay Rathinam, Assistant Professor of Immunology, Ph.D., Michigan State University.  Understand the immunologic basis of infectious and inflammatory diseases.

Ernst Reichenberger, Professor of Reconstructive Sciences, Ph.D., University of Erlangen.  Our laboratory is interested in the complex processes required for generating and maintaining skin and bones.  We study rate human genetic disorders where such mechanisms are disrupted on a genetic and functional level from gene discovery to in vitro and in vivo models.

Paul Robson, JAX_icon Associate Professor of Genetics and Genome Sciences, Ph.D. University of Toronto. Single cell transcriptomics, primate/human early embryonic development, maternal-fetal medicine, fetal programming, pluripotent cell biology, regulatory networks, tumor heterogeneity, circulating tumor cells.

Vladimir Rodionov, Professor of Cell Biology, Ph.D., Moscow State University. Research in this laboratory is focused on molecular mechanisms of intracellular transport and organization of microtubule cytoskeleton.

Annabelle Rodriguez-Oquendo, Professor of Cell Biology, M.D., New Jersey Medical School. Genetic link between healthy HDL cholesterol, heart disease, and infertility in women.

Blanka Rogina, Associate Professor of Genetics and Genome Sciences, Ph.D., Zagreb University School of Medicine. Biology of aging including the molecular genetic determinants of aging and longevity.

Daniel W. Rosenberg, Professor of Medicine, Ph.D., University of Michigan. Molecular genetics of colorectal cancer; signaling pathways in the development of tumors; toxicogenomics.

Edward F. Rossomando, Professor of Craniofacial Sciences, D.D.S., University of Pennsylvania, Ph.D., Rockefeller University, M.S. (Management) Rensselaer Polytechnic Institute. Translational research, strategic management, entrepreneurship, management of innovation and technology, strategic management in the healthcare industry.

David Rowe, Professor of Reconstructive Sciences, Director of Center for Regenerative Medicine and Skeletal Development, M.D. University of Vermont. Identification and characterization of cells within the mesenchymal lineages that lead to formation and maintenance skeletal tissues. Murine models for assessing cell based therapies for regeneration of adult skeletal structures.

Yijun Ruan, JAX_icon Professor of Genetics and Genome Sciences, Ph.D., University of Maryland. Elucidating the structures and dynamics of all functional DNA elements in complex genomes through DNA sequencing analysis of genetic variations in genomes and transcriptomes.

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Juan C. Salazar, Professor of Pediatrics, M.D., Universidad Javeriana. Analysis of the immunologic interactions between syphilis and HIV and the pathogenesis of spirochetal diseases including Lyme disease.

Archana Sanjay, Assistant Professor of Orthopaedic Surgery, Ph.D., University of Bombay. Regulation of bone remodeling; osteoblast and osteoclast differentiation and function.

Mansoor Sarfarazi, Professor of Surgery, Ph.D., University of wales College of Medicine. Positional mapping and mutation analysis of human genetic disorders; primary open angle glaucoma, primary congenital glaucoma, synpolydactyly, dyslexia, mitral valve prolapse and ascending aortic aneurysm.

Adam Schuyler,  Assistant Professor of Molecular Biology and Biophysics, Ph.D., Johns Hopkins University. Computational modeling of molecular dynamics and allosteric activation; nonuniform sampling techniques for multidimensional NMR experiments.

Peter Setlow, Board of Trustees Distinguished Professor of Molecular, Microbial and Structural Biology, Ph.D., Brandeis University. Biochemistry of bacterial spore germination.

Linda Shapiro, Professor of Cell Biology; Ph.D., University of Michigan. Molecular mechanisms by which large cell surface peptidases regulate numerous pathologic processes ranging from angiogenesis, tumor cell invasion, chronic and acute inflammatory diseases and cardiovascular disease.

Boris Slepchenko, Associate Professor of Cell Biology, Ph.D., Ural State University.

Henry Smilowitz, Associate Professor of Cell Biology, Ph.D., Massachusetts Institute of Technology. Pre-clinical experimental therapeutics of cancer using glioma, intracerebral melanoma, as well as breast, head & neck and bladder cancer models.   A.) Gold nanoparticles as radiation enhancers (with an emphasis on glioma), B.) Gold and iron nanoparticles for hyperthermia and hyperthermia mediated radiation enhancement (with an emphasis on head & neck cancer), C.) Combination of radiation therapy and immunotherapy for intracerebral tumors.

Pramod K. Srivastava, Professor of Medicine, Ph.D., Center for Cellular and Molecular Biology, Hyderabad, India. Heat shock proteins as peptide chaperones, roles in antigen presentation and applications in immunotherapy of cancer, infectious diseases and autoimmune disorders.

Michael Stitzel, JAX_icon Assistant Professor of Genetics and Genome Sciences, Ph.D., Johns Hopkins University. Human pancreatic islet cells and the genetic and environmental bases of type 2 diabetes.

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Mark R. Terasaki, Associate Professor of Cell Biology, Ph.D., University of California, Berkeley. Mechanism of nuclear envelope breakdown; structure and function of the endoplasmic reticulum.

Suzy V. Torti, Professor of Molecular Biology and Biophysics, Ph.D., Tufts University. Regulation of iron metabolism and the relationship between iron and cancer.

Feliks (Ephraim) Trakhtenberg, Assistant Professor of Neuroscience, Ph.D., University of Miami. Molecular mechanisms of neuronal development and regeneration in the CNS.

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Duygu Ucar, JAX_icon Assistant Professor of Genetics and Genome Sciences, Ph.D., Ohio State. Developing computational models to take advantage of existing datasets to study the dynamics and mechanisms of transcriptional gene regulation and propose testable hypotheses.

Derya Unutmaz, JAX_icon Professor of Immunology,  M.D., Mamara University Medical School. Decoding the functional and differentiation programs of different human T lymphocyte subsets. Developing various approaches towards development of T cells for cancer immunotherapy, HIV infection and regeneration during aging. Mapping the immune profiles in cancer, HIV and other inflammatory diseases to translate this knowledge as potential diagnostics.

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Anthony T. Vella, Professor of Immunology, Ph.D., Cornell University. T-cell immunity; costimulation; adjuvants and cytokines.

Paola Vera-Licona, Assistant Professor of Cell Biology, Ph.D., Virginia Polytechnic Institute and State University. Computational Systems Biology of Cancer, reverse-engineering of biological networks, network theory, development and application of algorithms for mathematical modeling and analysis of biological networks, and discovery and development of combinations of targeted therapies.

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David M. Waitzman, Associate Professor of Neurology, M.D., Ph.D., Mount Sinai School of Medicine and CUNY. Neurophysiology; oculomotor system; modeling of CNS.

Kepeng Wang, Assistant Professor of Immunology, Ph.D., Hong Kong University of Science and Technology. Understanding the role of IL-17 in the development, immune regulation, and treatment of colorectal cancer.

Zhao-Wen Wang, Associate Professor of Neuroscience, Ph.D., Michigan State University. Cellular and molecular mechanisms of neurotransmitter release; potassium and calcium channel function; Synaptic localization of potassium channels.

James Watras, Associate Professor of Medicine, Ph.D., Washington State. The mechanisms by which the sarcoplasmic reticulum regulates intracellular calcium concentration in vascular smooth muscle.

Chia-Lin WeiJAX_icon Director of Genome Technologies, The Jackson Laboratory for Genomic Medicine, Ph.D., University of California-Davis. Developing genomic and sequencing technologies and applying them to interrogate genomic and epigenomic elements pertinent to genome function and biology.

George Weinstock, JAX_icon Professor of Genetics and Genome Sciences, Associate Director for Microbial Genomics [Professor], The Jackson Laboratory for Genomic Medicine, Ph.D., Massachusetts Institute of Technology.

Sandra K. Weller, Professor of Molecular Biology and Biophysics, Ph.D., University of Wisconsin. Molecular genetics and biochemistry of herpes simplex virus DNA replication.

Bruce A. White, Professor of Cell Biology, Ph.D., Berkeley. Aspects of prolactin and growth hormone gene expression in the rat pituitary and rat pituitary tumor cell lines.

Adam Williams, JAX_icon Assistant Professor of Genetics and Genome Sciences, Ph.D., University College London. The role of non-coding RNAs in regulating gene expression relating to immune cell function, in particular, CD4+ T cells.

George Y. Wu, Professor of Medicine, Chief, Hepatology Section, Herman Lopata Chair in Hepatitis Research, M.D./Ph.D., Albert Einstein College of Medicine. Targeted delivery of biological substances specifically to liver cells, viral hepatitis B and C, steatohepatitis, and mitochondrial damage in liver diseases. Details of HCV replication, immunocompetent rat model of HCV infection, targeted DNA delivery, and targeted transplantation of mitochondria to hepatocytes.

Yi Wu, Assistant Professor of Genetics and Genome Sciences, Ph.D., Northwestern University.  Developing quantitative imaging tools that are capable of revealing dynamics of cellular signaling at high spatial and temporal resolution (biosensors), or that enable optical control of signaling proteins at precise times and subcellular locations (optogenetics).

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Siu-Pok Yee, Assistant Professor of Genetics and Genome Sciences, Ph.D., McMaster University. Specialties include molecular biology, mouse genetics and mouse developmental biology.

Erin Young, Assistant Professor of Genetics and Genome Sciences, Ph.D., Kent State University. The understanding of gene x environment interactions on pain outcomes, with a particular focus on stress and injury/inflammation as environmental factors.

Ji Yu, Associate Professor of Genetics and Genome Sciences, Ph.D., University of Texas-Austin. Optical imaging technology; regulation mechanisms in dendritic RNA translation; cytoskeletal dynamics.

Lixia Yue, Associate Professor of Cell Biology, Center for Cardiology and Cardiovascular Biology, Ph.D., McGill University. TRP channels and Ca2+ signaling mechanisms; Physiological and pathological functions of TRP channels in heart, brain, and kidney.

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Nada Zecevic, Professor of Neuroscience, M.D., Ph.D., University of Belgrade, Yugoslavia. Cellular and molecular aspects of CNS development; primate cerebral cortex; microglia; multiple sclerosis.

Beiyan Zhou, Associate Professor of Immunology, Ph.D., Northwestern University. Understanding the systemic network governed by epigenetic factors in immune cell development and function in obesity, incorporating animal models and OMICs-technologies to address the critical questions in the field, including mechanisms underlying histone modification factors and non-coding RNAs in modulating tissue specific stem cell features and immune cell interactions within the host tissue niche.

 

JAX_icon=The Jackson Laboratory for Genomic Medicine affliated faculty

 

rev. 8/17