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Dmitry Korzhnev’s Lab

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Author: Irina Bezsonova

Emilie Korchak receives Uplifting Athletes investigator award

Posted on January 27, 2026January 27, 2026 by Irina Bezsonova

UConn Health Postdoc a Projected Top-10 Draft Pick

Emilie Korchak is a postdoctoral fellow at UConn Health. (Tina Encarnacion/UConn Health photo)

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Congrats to the team on 2 back-to-back manuscripts in PNAS!

Posted on October 15, 2025October 15, 2025 by Irina Bezsonova

Small-molecule allosteric activator of ubiquitin-specific protease 7 (USP7).
Functional spectrum of USP7 pathogenic variants in Hao-Fountain syndrome: Insights into the enzyme’s activity, stability, and allosteric modulation.

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Hao-Fountain Syndrome Symposium & Family Conference in Nashville

Posted on October 15, 2025 by Irina Bezsonova

Dr. Korchak presented her work on functional characterization and rescue of USP7 variants associated with Hao-Fountain syndrome.

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Congrats to Emilie Korchak on becoming Dr. Emilie Korchak!

Posted on October 15, 2025October 15, 2025 by Irina Bezsonova

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Congrats to Emilie and Dane on their new publication in JMB

Posted on June 24, 2025 by Irina Bezsonova

The C-Terminal Tail of Ubiquitin-Specific Protease 7 Facilitates Ubiquitin Release and Ensures Efficient Catalytic Turnover.

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Dane & Sydney’s wedding day celebration

Posted on June 24, 2025June 24, 2025 by Irina Bezsonova

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Publication Highlight

Posted on May 30, 2025June 24, 2025 by Irina Bezsonova

How a Key Enzyme Switches On and Off—And How a Rare Mutation Pushes It Into Overdrive

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New publication in PNAS

Posted on May 30, 2025June 24, 2025 by Irina Bezsonova

Activation dynamics of ubiquitin-specific protease 7

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Our new publication in the Journal of Biological Chemistry

Posted on May 30, 2025June 24, 2025 by Irina Bezsonova

Differences in structure, dynamics, and zinc coordination between isoforms of human ubiquitin ligase UBE3A

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MBB Student SciArt contest

Posted on March 27, 2024March 27, 2024 by Irina Bezsonova

Gianluca Arianna, Dane Geddes-Buehre and Daniel Fairchild participated in the 3rd MBB Student SciArt Contest.

Check out their creative works!

The Impossible Helix by Daniel Fairchild (woodwork)

E. coli Hard at Work (3D printing) by Dane Geddes-Buehre

Veins and Arteries by Gianluca Arianna (watercolor)

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Bezsonova Lab
Department of Molecular Biology and Biophysics
UConn Health
263 Farmington Avenue
Farmington, CT 06032-3305

Phone: 860-679-2769
Fax: 860-679-3408
Email: bezsonova@uchc.edu

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