Welcome to our lab!
Ubiquitin Biology and Cancer
Protein Structure/Function Relationship
Accepting applications from rotation students and graduate students.
Our USP7 work was featured in the Cell Chemical Biology Preview The Next Step Forward in Ubiquitin-Specific Protease 7 Selective Inhibition Matthieu Desroses, Mikael Altun Ubiquitin-specific protease 7 is a validated anticancer target; thus, selective USP7 inhibitors are of great interest. In this issue of Cell Chemical Biology, Lamberto et al. (2017) and Pozhidaeva et al. (2017) report […][Read More]
Check out our artwork featured on the cover of the December ’17 issue of the Cell Chemical Biology![Read More]
Congrats to Thomas Bregnard on his first paper “Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60” published in PLoS One today! check it out[Read More]
Check out this editorial by Milka Kostic on our latest USP7 paper: “We DUB thee… Druggable?”[Read More]
Congrats to Sasha and Gabi on their USP7 inhibition paper being accepted to Cell Chemical Biology![Read More]
Congrats to Dmitry on his new NIH R01 grant![Read More]
Congrats to Dmitry on publication of a review article on Protein folding by NMR in Progress of Nuclear Magnetic Resonance Spectroscopy![Read More]