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Welcome to our lab!

Bezsonova Lab Photo

Research Interests:

  • Ubiquitin Biology and Cancer

  • Epigenetics

  • Structural Biology

  • Protein Structure/Function Relationship

  • NMR Spectroscopy

  • X-ray Crystallography

Accepting applications from rotation students and graduate students.

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Our USP7 work was featured in the Cell Chemical Biology Preview  The Next Step Forward in Ubiquitin-Specific Protease 7 Selective Inhibition Matthieu Desroses, Mikael Altun Ubiquitin-specific protease 7 is a validated anticancer target; thus, selective USP7 inhibitors are of great interest. In this issue of Cell Chemical Biology, Lamberto et al. (2017) and Pozhidaeva et al. (2017) report […]

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Check out our artwork featured on the cover of the December ’17 issue of the Cell Chemical Biology!

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Congrats to Thomas Bregnard on his first paper “Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60” published in PLoS One today! check it out    

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Check out this editorial by Milka Kostic on our latest USP7 paper: “We DUB thee… Druggable?”  

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Congrats to Sasha and Gabi on their USP7 inhibition paper being accepted to Cell Chemical Biology!  

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Congrats to Dmitry on his new NIH R01 grant!  

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Congrats to Dmitry on publication of a review article on Protein folding by NMR in Progress of Nuclear Magnetic Resonance Spectroscopy!

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