Principal Investigators

Irina Bezsonova, Ph.D.

Irina Bezsonova, Ph.D.
860-679 2769

Dmitry Korzhnev, Ph.D.

Dmitry Korzhnev, Ph.D.

Current Students

Gabrielle Valles, Ph.D. student

Gabrielle Valles, Ph.D. student

Gabi works on structural and functional characterization of USP7 as a target for cancer therapies.

Alessandro Rizzo, M.S.

Alessandro Rizzo, M.S., Ph.D. student

Alex studies mechanisms of assembly of multi-protein TLS complexes.

Thomas Bregnard, M.S., Ph.D. student

Thomas studies structure of Promyelocytic Leukemia Protein (PML) and its self-assembly into PML-nuclear bodies in response to viral infections and other cellular stress.

Socheata LimSocheata Lim, Ph.D. student

Socheata works on dynamics and interactions of beta-clamp proteins in bacterial DNA replication.

Tima Karginov, rotating M.D./Ph.D. student

Tima studies deubiquitinating enzyme USP7.

Kerry Silva, rotating Ph.D. student

Kerry works on characterization of protein interaction network in DNA Translesion Synthesis in yeast.

Former Postdoctoral Fellows

Yulia Pustovalova, Ph.D. (currently at University of Gothenburg, Sweden)
Structural characterization of Translesion Synthesis (TLS) DNA Polymerases

Mariana Quezado, Ph.D. (currently at Universidade Federal do Rio Grande do Sul
Belo Horizonte, Minas Gerais, Brazil)
Structural characterization of human Helicase-Like Transcription Factor (HLTF)

Former Students


Alexandra Pozhidaeva, Ph.D. student (currently a postdoctoral fellow at UMass)
Structural characterization of human ubiquitin specific protease USP7


Sherif Eldirany, Undergraduate Student (currently at Yale Medical School)
NMR studies of human Helicase-Like Transcription Factor (HLTF) HIRAN domain
Histone ubiquitination by Polycomb Repressive Complex 1 (PRC1)

Paige Salerno, Undergraduate Student (WPI)
TLS Polymerases


Kirsten Salline, Undergraduate Student (Cornell University)
Structural characterization of C-terminal domains of USP7

Maciej Kosakowski, Undergraduate Student (UConn)           
NMR studies of TLS Polymerases


Brianna Munoz, Undergraduate Student (Providence College)
NMR studies of Polycomb Repressive Complex 1 (PRC1)