Author: Sheryl Rosen

Methods for Analyzing Time-to-Event Survival Data Short Course

We are excited to announce a biostatistics short course scheduled for late May featuring Miranda Lynch, Ph.D., assistant professor of community medicine and health care with assignments in the Center for Quantitative Medicine and the Biostatistics Center within CICATS. This short course surveys statistical approaches to analyzing time-to-event survival data which is frequently encountered in biomedical studies and clinical trials. Through lectures and hands-on computer exercises, the course will provide researchers with techniques for analyzing and interpreting survival data using survival curves and Kaplan-Meier estimators of survival functions, as well as regression methods (i.e. Cox proportional hazards regression).

It’s About Time: Methods for Analyzing Time-to-Event Survival Data
Wednesday, May 28 at 9 a.m.
UConn Health in Farmington, Connecticut

Bioinformatics Short Course on Expression Microarray Analysis

We are offering an exciting bioinformatics short course lead by Julia Chifman, Ph.D., at Wake Forest University School of Medicine aimed at University, Hospital and Industry based biomedical and translational researchers, educators, and clinician-scientists who are interested in bioinformatics tools and data analysis methodologies specific to gene expression microarrays, e.g., Affymetrix® or Illumina® platforms.

Introduction to Expression Microarray Analysis Using R/Bioconductor
Friday, May 2 at 9 a.m.
Lyman Maynard Stowe Library at UConn Health in Farmington, Connecticut

Center for Quantitative Medicine Website Launches

Dr. Reinhard Laubenbacher and the Center for Quantitative is pleased to announce the launch of its website The site brings the Center to Quantitative Medicine into cyberspace and was developed in partnership with the UConn Health Office of Communications. The Center for Quantitative Medicine website is designed to share information about the center’s research and education initiatives and to introduce its faculty to the UConn Health, UConn-Storrs, Jackson Laboratory for Genomic Medicine, and broader research community.

The site includes an event calendar and news feed, provides links to the CQM social media accounts, and provides information about the center, its history, work, and faculty and staff.

Please check out the site at and let us know what you think!

Anatomy & Physiology of EHRs Short Course on February 1

The Center for Quantitative Medicine is offering an intensive one day short course taught by a multidisciplinary team of physician-educators and informatics leaders that uses a patient case approach to introduce the structure and function  of electronic health records (EHR) systems and illustrates these key health informatics.

Concepts discussed during the course include:

  • Data acquisition, storage, and retrieval,
  • electronic health information exchange (HIE),
  • clinical decision support, and
  • reporting EHR data for quality improvement, meaningful use, performance and Accountable Care Organizations (ACOs).

An ONC certified complete EHR system will be shown to demonstrate  these important topics.

Date: Saturday, February 1, 2014
Time: 10 to 4 p.m.
Location: 195 Farmington Avenue, Suite 210, Farmington, CT

Learn more at

New Co-Director Named at Center for Quantitative Medicine

Reinhard Laubenbacher
Reinhard Laubenbacher, co-director of the Center for Quantitative Medicine. (Lanny Nagler for UConn Health Center)

In his own words, Reinhard Laubenbacher, co-director of the UConn Health Center’s new Center for Quantitative Medicine, experienced an “academic midlife crisis” 11 years ago when his career path began to shift from mathematics to systems informatics and other applications to advance biomedical research.

An accomplished and internationally recognized mathematician and systems biologist, Laubenbacher now holds the first joint academic appointment with the Health Center and The Jackson Laboratory for Genomic Medicine.

“Joining the UConn Health Center and Jackson allows me to continue my migration to more applied research and to make a difference in the lives of patients,” he says.

While he still holds a deep appreciation for the “art of mathematics,” his focus now is implementing mathematical algorithms and related software to support research connected to biomedical problems, including genomic and other approaches to personalized medicine.

“There are three legs to our work,” Laubenbacher explains. “We begin by developing mathematical algorithms in systems biology; then implement those algorithms into software and, lastly, apply the software to help researchers looking at a specific biomedical question.”

“Dr. Laubenbacher has the right skill sets to support growth in systems biology and bioinformatics at the Health Center, especially as we embark on several collaborative research endeavors with our colleagues at The Jackson Laboratory for Genomic Medicine,” adds Dr. Frank Torti, the Health Center’s executive vice president for health affairs and dean of the UConn School of Medicine.

The non-profit Jackson Laboratory for Genomic Medicine brings together researchers, clinicians, pharmaceutical developers and other members of the bioscience community to discover the precise genomic causes of disease, develop individualized solutions and help build Connecticut’s bioscience industry. The organization, based in Bar Harbor, Maine, is building a new 189,000 square-foot research institute on the campus of the UConn Health Center in Farmington that will open in the fall of 2014.

“Biology is progressively becoming a quantitative science that requires mathematical strategies to unravel its secrets,” explains Dr. Edison Liu, president and CEO of The Jackson Laboratory. “Dr. Laubenbacher brings critical expertise and senior leadership to our efforts in genomic medicine. Reinhard will also be a catalyst for deep interactions between The Jackson Laboratory for Genomic Medicine and the University of Connecticut Health Center. We are absolutely thrilled to have him join us.”

Of the 30 principal investigators to be hired by 2020 at JAX Genomic Medicine, Laubenbacher is the first of 10 who will be jointly appointed with UConn.

“Through the new Center for Quantitative Medicine, we’re creating an intellectual home for quantitative approaches to medicine, bringing together areas such as quantitative biology, genomics, bioinformatics, biostatistics and biomedical informatics, in particular the analysis of large data sets. We will connect with clinical researchers to help drug development and testing efforts, using the broad range of expertise the center will assemble,” Laubenbacher explains. The other co-director, he says, will have more of a clinical or public health background and together, they will support a range of research initiatives.

Laubenbacher previously served as professor and director of education and outreach at the Virginia Bioinformatics Institute, part of Virginia Polytechnic Institute and State University (Virginia Tech). He was also a tenured professor in the Virginia Tech Mathematics Department, an affiliate faculty of biomedical engineering and sciences at Virginia Tech as well as Wake Forest University, and an adjunct professor in the Department of Cancer Biology at the Wake Forest University School of Medicine.

Before joining the Virginia Bioinformatics Institute – a pivotal change in his career direction – he was a professor of in the Department of Mathematical Sciences at New Mexico State University.

“I became interested in the history of mathematics, which led me to think more deeply about the contributions our own work makes to the lives of others,” he says of the motivation for his career shift.

At UConn, Laubenbacher is also a professor in the Department of Cell Biology, and an adjunct professor in the Mathematics Department on the Storrs Campus. He is continuing his research endeavors with Dr. Torti and is already establishing other collaborations on campus. But for now, his top priority is recruitment and team building for the new center. “With the right team and the right culture, we will create an environment where quantitative and clinical experts can collaborate effectively,” he adds.

Laubenbacher is a graduate of the University of Munich and earned advanced degrees in mathematics from Indiana University and Northwestern University. He has received numerous teaching and scholarly awards throughout his career, including a Fulbright Scholarship and becoming a fellow of the American Mathematical Society. In addition, Laubenbacher is widely published in scholarly journals in areas including computational biology, systems biology, mathematical foundations of computer simulation, and more.