Congrats to the team on 2 back-to-back manuscripts in PNAS! Posted on October 15, 2025October 15, 2025 by Irina Bezsonova Small-molecule allosteric activator of ubiquitin-specific protease 7 (USP7). Functional spectrum of USP7 pathogenic variants in Hao-Fountain syndrome: Insights into the enzyme’s activity, stability, and allosteric modulation.