Distribution of Human Pluripotent Stem Cell Lines

The UConn Stem Cell Core has human embryonic stem cell lines (hESC lines) and human induced pluripotent stem cell lines (hiPSC lines). We have four hESC lines, and several hiPSC lines.

  • Human embryonic stem cell (hESC) lines: CT-1, CT-2, CT-3, and CT-4.

CT lines were derived at the UConn Stem Cell Core and are NIH approved. They have also been accepted to the UK Stem Cell Bank.

There are four lines, and the NIH approval names are the same as our names. CT-2 is the most widely used of the four lines.

Contact us to request CT hESCs.

Sample of Publications using CT hESCs

Progresses and challenges in optimization of human pluripotent stem cell culture

Human embryonic stem cell derivation, maintenance, and differentiation to trophoblast

Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells

Slice culture method for studying migration of neuronal progenitor cells derived from human embryonic stem cells (hESC)

Increasing doublecortin expression promotes migration of human embryonic stem cell‐derived neurons

hiPSCs from UConn Stem Cell Core

Cell Line Name Other names Sample Method/Factors Publications or Notes on method XX or XY Karyotype Availability
UCH-HF-YK-27 HDFa-YK27, YK27 Human dermal fibroblast line hDFa Retroviral, see  Martins-Taylor, et al., 2011 Martins-Taylor, et al., 2011  Reference XX Yes Yes
UCH-HF-YK-26 HDFa-YK26, YK26 Human dermal fibroblast line hDFa Retroviral, see  Martins-Taylor, et al., 2011 Martins-Taylor, et al., 2011  Reference XX Yes Yes, high passage only
UCH-HF-TZ-1 IMR90-TZ1, TZ-1 Human fetal lung fibroblast line IMR90 Lentiviral, see  Martins-Taylor, et al., 2011 Zeng, et al., 2010  Reference XX Yes Yes
UCH-HF-47- RX47I-RIP1, RiP1, RX47 Human neonatal foreskin fibroblast line BJ mRNA/OCT4, SOX2, KLF4, C-MYC, and LIN28 Stemgent Inc. method and fibroblasts  Reference XY Yes Yes, needs scale up
UCH-CBLR-48A- CBLR, RX48A,  CB-iPS-lenti

 

Human cord blood MNC. Lonza stemcca – lentiviral Vector by G. Mostoslavsky  Reference XX Yes Yes, needs scale up
UCH-CBY4-48B- CBY4, RX48B,  CB-iPS-epi Human cord blood MNC, Lonza Episomal/ OCT4, SOX2, KLF4, L-MYC, LIN28, and P53-shRNA Method by S. Yamanaka  Reference XX Yes Yes, needs scale up
UCH-PBY4-48D- PBY4, RX48D,  PB-iPS Human peripheral blood MNC Episomal/ OCT4, SOX2, KLF4, L-MYC, LIN28, and P53-shRNA Method by S. Yamanaka Reference XY Yes Yes, needs scale up
UCH-HF-49A- HFY4, RX49A,  hFib_epi

 

Human adult skin fibroblasts, Lonza Episomal/ OCT4, SOX2, KLF4, L-MYC, LIN28, and P53-shRNA Method by S. Yamanaka Reference XX Yes Yes, needs scale up
UCH-PB-48E- PB-BD1-Y4,  PB-iPS-BD1,

RX48E

Peripheral blood from draw Episomal/ OCT4, SOX2, KLF4, L-MYC, LIN28, and P53-shRNA Method by S. Yamanaka Reference XY Yes Yes, needs scale up
UCH-HF-121- BJY4 FF (feeder free),  RX121

 

Human neonatal foreskin fibroblast line BJ, ATCC Episomal/ OCT4, SOX2, KLF4, L-MYC, LIN28, and P53-shRNA Derived in E7, E8, matrigel, frozen in mFreSR. Vectors by S. Yamanaka Reference XY No Yes, needs thaw, scale up, karyotype
UCH-HF-63- BJSV,  RX63

 

Human neonatal foreskin fibroblast line BJ, ATCC Cytotune Sendai Virus, OSKM Method  Reference (Version 1) XY No Yes, needs thaw, scale up, karyotype
UCH-HF-12- BJRV,  RX12

 

Human neonatal foreskin fibroblast line BJ retroviral OSKML XY No Yes, needs thaw, scale up, karyotype
UCH-HF-13- BJLV,  RX13

 

Human neonatal foreskin fibroblast line BJ stemcca – lentiviral Vector by G. Mostoslavsky  Reference XY Yes Yes, needs thaw, scale up, karyotype
UCH-HF-YZ-1 IMR90-YZ1, YZ-1 Human fetal lung fibroblast line IMR90 Retroviral, see  Martins-Taylor, et al., 2011 Martins-Taylor, et al., 2011  Reference XX No Yes, needs thaw, scale up, karyotype

About the hiPSC Names

UCH-[internal descriptor]-[log number]-[clone number, may be blank]

UCH = UConn Health

Please contact us to request hiPSCs from UConn Stem Cell Core., or with questions about our hiPSC lines.

Sample of publications using UConn Stem Cell Core hiPSCs

Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells

Efficient differentiation of human iPSC‐derived mesenchymal stem cells to chondroprogenitor cells

The familial Alzheimer’s disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons

One-step derivation of mesenchymal stem cell (MSC)-like cells from human pluripotent stem cells on a fibrillar collagen coating

Establishment of human cell type-specific iPS cells with enhanced chondrogenic potential

Modified hyaluronan hydrogels support the maintenance of mouse embryonic stem cells and human induced pluripotent stem cells

Human pluripotent stem cells have a novel mismatch repair-dependent damage response

Comparison and optimization of hiPSC forebrain cortical differentiation protocols

Single-Cell Detection of Secreted Aβ and sAPPα from Human IPSC-Derived Neurons and Astrocytes

Role of DNMT3B in the regulation of early neural and neural crest specifiers

Concise review: genomic stability of human induced pluripotent stem cells

Vaccination with human pluripotent stem cells generates a broad spectrum of immunological and clinical responses against colon cancer

Inhibition of caspase-mediated anoikis is critical for basic fibroblast growth factor-sustained culture of human pluripotent stem cells

The Balance of Positive and Negative Effects of TGF-β Signaling Regulates the Development of Hematopoietic and Endothelial Progenitors in Human Pluripotent Stem Cells

Cooperative Effect of Erythropoietin and TGF‐β Inhibition on Erythroid Development in Human Pluripotent Stem Cells