Using integrated single-cell RNA and ATAC analyses, we resolved developmental trajectories of cerebellar progenitors, identified putative trans- and cis-elements that control cell state transition, and reverse-engineered gene regulatory networks of each cerebellar cell type. Check out the links to the paper and the datasets and computer codes.
A new manuscript on integrated single-cell RNA- and ATAC-seq analysis of embryonic mouse cerebellum is out. Check out the preprint on bioRxiv.
A new five-year research grant is awarded by NIH to study the combinatorial function of Foxp1/2/4 in Purkinje cell diversification and cerebellar development.