The UConn Cell and Genome Engineering Core provides comprehensive support for human pluripotent stem cell research. We distribute in-house hESC lines (CT1–CT4) and WiCell lines (H1, H9), and offer quality control services such as mycoplasma testing and pluripotency validation.
Our biobanking program securely stores and distributes custom iPSC lines and serves as a major repository for the Foundation for Prader-Willi Research and the Angelman Foundation. We offer integration-free iPSC reprogramming using Sendai virus from multiple tissue sources under feeder or feeder-free conditions.
Our Genome Editing team uses cutting-edge TALEN and CRISPR technologies to provide precise, scarless genome engineering, including the creation of isogenic pairs, mutation correction, and the development of reporter lines. We support complete project workflows or targeted assistance.
Located in the Cell and Genome Sciences Building, at 400 Farmington Ave, Farmington, CT, the Core has access to dedicated lab space, biobanking facilities, tissue culture rooms, microscopes, and shared common equipment.