Month: April 2017

Dr. Thanh Nguyen Joins the IRE

By Cato T. Laurencin, M.D., Ph.D.

Dr. Thanh Nguyen Joins the IREThe Institute for Regenerative Engineering welcomes Assistant Professor Thanh Nguyen. Dr. Nguyen joined the Departments of Mechanical Engineering and Biomedical Engineering at UConn at the beginning of 2016. His research is highly interdisciplinary and at the interface of biomedicine, materials and nano/micro technology. He did his postdoctoral fellowship with Dr. Robert Langer at MIT. His postdoctoral research involved developing a platform technology which can create 3-dimensional microstructures of biomaterials, such as biodegradable and FDA-approved polymers for applications in vaccine/drug delivery and medical implants. In 2013, Dr. Nguyen obtained his PhD from Princeton University in the department of Mechanical and Aerospace Engineering. There he worked with Dr. Michael McAlpine to develop the field of Biointerfaced Nanopiezoelectrics, which aims to create advanced electromechanical materials/devices at nanoscales that can interface with biological cells/tissues for applications in harvesting, sensing and engineering cellular mechanics. His work has been published in prestigious journals and highlighted in major media such as The New York Times and Nature.

2017 Moorehead-Laurencin Sex and Gender Research Forum

By Cato T. Laurencin, M.D., Ph.D.

2017 Moorehead-Laurencin Sex and Gender Research ForumThe Helen I. Moorehead-Laurencin, M.D., Sex and Gender Research Forum is a very important program of the Institute for Women’s Health and Leadership at Drexel University. This year’s forum took place on March 8, International Women’s Day. This interactive program highlighted Drexel’s interdisciplinary research focused on sex and gender in a local, national and global context. I was excited to give the forum’s opening speech and introduce my beloved late mother, Dr. Helen Laurencin, to the attendees. It was well attended by students, faculty, and staff who represented several different schools and colleges at Drexel, as well as many members of the community. The Forum also received media coverage from the local ABC affiliate, WPVI-TV.

I want to congratulate the Institute for Women’s Health and Leadership at Drexel for putting on such a fine forum. View the Forum.

Regenerative Engineering Solutions to Rotator Cuff Tears

By Cato T. Laurencin, M.D., Ph.D.

Regenerative Engineering Solutions to Rotator Cuff TearsRotator cuff tears represent a large proportion of musculoskeletal injuries attended by clinics, thereby making rotator cuff repair surgeries one of the most widely performed musculoskeletal procedures. Despite the high incidence rate of rotator cuff tears, operative treatments have provided minimal functional gains and suffer from high re-tear rates.

I am happy to report that recent data from the Institute for Regenerative Engineering suggest that the regenerative engineering technique can be useful for improved healing of torn rotator cuff tendons. Specifically, our team used a nano-based biomaterial matrix conducive to growing stem cells, and combined it with adult stem cells. The results are promising, but our group must continue working for some time before the process can be applied to humans. Our results were published in the prestigious journal PLoS One earlier this month. The paper represents a novel treatment paradigm for the treatment of massive rotator cuff tendon tears. In addition, our work has been highlighted by the NIH Research Matters. Thanks to the NIH, the NSF and the Raymond and Beverly Sackler Foundation for their support of our work.

The Kavli Foundation Increases Investment in CICATS

By Cato T. Laurencin, M.D., Ph.D.

I am happy to announce The Kavli Foundation has renewed and increased its investment in the Connecticut Institute for Clinical and Translational Science (CICATS). The Foundation supports CICATS Science Cafes, principally through the Kavli BRAIN Coffee Hour Program. These programs are led by CICATS’ Core Interest Groups and are designed to engage a broad range of scientists and generate interactive discussions. Spurred by CICATS’ initial success, the grant from The Kavli Foundation ensures the cafes will continue and expand, pursuing advanced scientific knowledge and research, especially Convergence Research. I want to thank The Kavli Foundation for its unwavering support of our programs here at UConn Health.

Distinguished Professor at Widener University

Distinguished Professor at Widener University

By Cato T. Laurencin, M.D., Ph.D.

On April 4, I was really honored to be the keynote speaker for the 2017 Distinguished Professor Lecture Series at the Widener University School of Engineering. During my talk, I shared my insights on “regenerative engineering” – the convergence of advanced materials science, stem cell science, physics, developmental biology, and clinical transition. Particularly, I focused on our current work on musculoskeletal tissue regeneration using polymeric nanofiber systems and stem cells. Thank you to Dr. Fred Akl, dean of the School of Engineering, and Dr. Rudy Treichel, associate dean, for hosting such a visit and lecture for me.