Month: February 2013

Top Research Article in the Journal of Biomedical Materials Research

 Progress in BiomaterialsThe Journal of Biomedical Materials Research (JBMR) has just published its 100th volume, Progress in Biomaterials, which features the top 25 papers it has published in its 50+ years. I am happy to report that one of our lab’s papers, “Electrospun nanofibrous structure: A novel scaffold for tissue engineering” was selected for inclusion. This article has been cited more than 1100 times. According to JBMR, the major criteria for inclusion of papers in this virtual issue was “the identification of articles that, in their time, were considered novel, original, state-of-the-art, groundbreaking, led to clinical application, and opened new areas of biomaterials research.” The editors commented “this pioneering paper by Laurencin showed that biodegradable electrospun nanofiber structures were capable of supporting cell attachment and proliferation and indicated that cells seeded on this structure could maintain phenotypic shape and guide growth according to nanofiber orientation.” Perhaps even more exciting, the editors chose figure 2 of our paper for the cover of the 100th Volume Celebration Edition.

Congratulations to all.

Image was adpated from

The Institute for Regenerative Engineering Welcomes New Fellow, Roshan James, Ph.D.

Roshan James, Ph.D.I am pleased to announce that Dr. Roshan James recently joined the Institute for Regenerative Engineering as a postdoctoral fellow. His current research focuses on the design and fabrication of novel biomaterials for musculoskeletal tissue engineering. His research interests include biomaterials, integrated tissues, and regenerative engineering.

Dr. James received his bachelor degree from the Indian Institute of Technology, Kharagpur in India, and completed his doctoral thesis under my mentorship at the University of Virginia (UVa) in 2012. His Ph.D. thesis focused on the design of mechanically competent polyester-based matrices for tendon tissue regeneration. In addition, he worked on developing a growth factor delivery system that provided bioactive physiologically relevant doses to modulate cellular responses in adipose stromal cells along the tendonogenic lineage.

Dr. James received a number of awards from UVa where he presented at university-wide research competitions. In, 2012, he was a finalist in the UVa Presidential Research Competition. In addition, he was recently selected as a New Investigator Recognition Awards (NIRA) finalist at the 2013 Orthopaedic Research Society Conference in San Antonio. His talk was entitled ‘Combined Treatment of a Tendon Gap with a Biomimetic Electrospun Scaffold, Stromal Cells and GDF5,’ and his presentation focused on in vivo characterization of biodegradable biomaterials designed to mimic the structure of the tendon extracellular matrix.

Tendon gap PowerPoint screenIt is worth noting that Dr. James has made a significant impact on tendon tissue engineering. He has successfully developed a novel tubular scaffold system to regenerate a large gap defect in tendon tissue due to severe injuries. The scaffold system can also deliver adipose stromal cells and growth factors that facilitate the regenerative process resulting in new tendon tissue formation.

Everyone in the Institute for Regenerative Engineering welcomes Roshan and looks forward to working with him here at UConn.

The Institute for Regenerative Engineering Hosts Ronald W. Rousseau, Ph.D.

Ronald W. Rousseau, chair of the School of Chemical and Biomolecular Engineering at Georgia Institute of TechnologyTo further facilitate collaborations between UConn and internationally renowned experts, it was our great honor to host Ronald W. Rousseau, chair of the School of Chemical and Biomolecular Engineering at Georgia Institute of Technology. Dr. Rousseau, the Cecil J. “Pete” Silas Endowed Chair, delivered a talk entitled “Chirally Pure Pharmaceutical Products: The Role of Crystallization” in the Department of Chemical, Materials and Biomolecular Engineering at Storrs. His research focuses on separation processes and has resulted in more than 200 publications. Dr. Rousseau has received numerous awards including the prestigious Warren K. Lewis Award from the American Institute of Chemical Engineers (AIChE), the Clarence G. Gerhold Award from the AIChE’s Separations Division and the AIChE’s Forest Products Award. He is a fellow of both AIChE and the American Association for the Advancement of Science (AAAS). It was an honor having Dr. Rousseau at UConn, and we look forward to collaborating with him in the future.