Last week, I had the privilege of giving the opening invited speech for the Biomaterials and Tissue Regeneration Symposium at the Materials Research Society in Boston. I spoke about our Institute’s work in building matrices for bone regeneration using polymeric materials and ceramics. I focused on some of our new theories regarding the design of matrix systems that can be inductive for Bone. I want to thank my co-authors of this work and I also want to provide a special thanks to Professor Mei Wei who invited me to give the lecture at the meeting.