Helen Swede, Associate Professor in Public Health Sciences, was awarded a Research Excellence Program (REP) grant by the UConn Office of the Vice-President for Research entitled, “Outcome Disparities in Cancer: Adverse Events in African-American Patients with Sickle Cell Trait and Other Hemoglobinopathies”. This study will expand her prior work in breast and prostate cancers into several additional cancer types along with a deeper look into clinical factors associated with adverse events and mortality. Long thought to be a benign condition, SCT recently has been linked to an increasing number of medical conditions such as chronic kidney disease. This research domain has the potential for substantial translational value given that SCT is found in a far higher proportion of African-Americans compared to whites (8.5% vs 0.20%, respectively), and could explain persistent differences in survival rates. The documented link between SCT and chronic kidney disease is of great relevance in cancer treatment, as well, given the prospect of reduced clearance of powerful anti-cancer drugs – leading to toxicity and other sequalae. On this project, Dr. Swede will continue collaborations with researchers at Hartford Hospital, SUNY at Buffalo, Yale Cancer Center, and UConn Health.

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