The Central Electron Microscope Facility (CEMF) is a UConn Health-supported research facility providing electron microscopy research service for faculty, students and extramural users. The CEMF occupies approximately 1,800 sq. ft. of space on B level of the main UConn Health building (rooms AB027 and AB031). The CEMF has three recently installed electron microscopes (EMs) equipped with digital imaging capabilities: a Hitachi H-7650 transmission EM, a JEOL JSM-5900LV scanning EM and a Zeiss Sigma Gemini HV field emission Scanning EM. Sample preparation instruments include ultramicrotomes, vacuum evaporator, sputter coater, critical point dryer, high pressure freezer, freeze substitution system and ion beam coater. The electron microscopes and other instruments also are available for use by experienced faculty or students. Training is available on an individual basis or in a formal graduate course offered every other year.