Rebecca Page

Rebecca Page photoProfessor
Department of Cell Biology

Contact

Phone: 860-679-6045
Email: rpage@uchc.edu
Office: L5087

Page laboratory website

UConn Health
263 Farmington Avenue
Farmington, CT 06030

Research Interests

How we sense and react to our environment is communicated in the cell by vast networks of highly dynamic, interacting proteins. These interactions are regulated in both space and time, and it is this tight regulation that allows signals from outside of the cell to be rapidly and precisely transmitted to the nucleus leading to the appropriate, and healthy, cellular response. We integrate structural biology, cell biology, genetics and biochemistry in order to understand how these signals in both prokaryotes and eukaryotes are communicated in the cell at atomic resolution.

Page Model
SDS22 (left) binds PP1 (right) and maintains it in a fully inactive state until holoenzyme formation, preventing unregulated dephosphorylation by PP1.